Massive Bio has made its inaugural strategic investment in Rivvi. Read the announcement

Buyer's guide

Best clinical trial patient engagement,compared

Matching engines score who qualifies. Most eligible adults with cancer still never hear about a trial. The missing layer is the conversation that reaches them, screens them, and writes the outcome back.

HIPAA BAA · SOC 2 Type II · Adverse events routed

The short answer

Engagement is the gap, not matching

US adult cancer trial enrollment has sat near 3% to 5% for years. Identification systems can score thousands of records. Recruitment is whether a person is actually reached, in their language, before the window closes.

Decentralized trial platforms (Science 37, THREAD, Medable and peers) publish patient apps, ePRO, and televisits. Those are study-conduct tools. They do not, on the public record, run first-contact outreach across voice, text, and chat that writes status back to a hub or CRM.

Rivvi owns that conversation. Matching, including Massive Bio's prospectively validated oncology intelligence, decides who and why. Rivvi runs first contact, protocol pre-screening, and status write-back, and routes adverse events to the person you name. Clinical judgment stays with clinicians.

Side by side

Engagement layers, honestly compared

The columns that matter for a sponsor or hub: can you reach the matched patient today, and does the outcome land in your system of record.

rivvi
Typical DCT platform
Outsourced call center

Voice + text + web chat

rivvi

Yes

Typical DCT platform

App / ePRO / televisit

Outsourced call center

Voice, staffed

First-contact outreach on a match list

rivvi

Yes

Typical DCT platform

Not stated

Outsourced call center

Yes

Protocol pre-screening in conversation

rivvi

Yes

Typical DCT platform

In-app / site

Outsourced call center

Scripted

Writes status back to hub or CRM

rivvi

Yes

Typical DCT platform

Not stated

Outsourced call center

Varies

Adverse events routed on every path

rivvi

Yes

Typical DCT platform

Not stated

Outsourced call center

Human flag

HIPAA BAA before patient data moves

rivvi

Yes

Typical DCT platform

Varies

Outsourced call center

Varies

Public pricing

rivvi

Yes

Typical DCT platform

No

Outsourced call center

No

Self-serve trial for this job

Life sciences is enterprise-configured

rivvi

No

Typical DCT platform

No

Outsourced call center

No

Competitor details are drawn from each vendor's public pricing and product pages as of July 2026 and may change. "Not stated" means the vendor does not publish that detail. Rivvi's free-trial details reflect the current published offer at rivvi.ai/pricing and rivvi.ai/sign-up.

Questions

Clinical trial engagement, answered

Is Rivvi a decentralized trial platform?

No. Rivvi is the engagement layer that sits after matching. DCT platforms run study conduct: apps, ePRO, televisits, and site workflows. Rivvi reaches the matched patient, runs pre-screening, and writes the outcome back. Sponsors keep their matching engine and their DCT stack.

How does the Massive Bio partnership fit?

Massive Bio provides prospectively validated oncology intelligence. Rivvi is the agentic action layer that turns each match into governed outreach and coordination. The announcement is on the Rivvi blog and the original Business Wire of August 4, 2026.

Do we start on the free trial?

Life sciences programs are enterprise-configured: protocols, AE routing, and hub write-back are set with you. The public 14-day trial is for self-serve practice and pharmacy work. Talk to us and we show the same engagement layer on your own candidate list.

Does Rivvi diagnose or enroll a participant?

No. Rivvi does not diagnose, prescribe, or override clinical judgment. Qualified participants route to the site or navigator you name. People who are not ready stay warm. Every action is governed, auditable, and written back.

More on how the rules bind: Security and compliance

Show us the candidate list.

Life sciences programs are enterprise-configured. Tell us what you're running and we'll show the engagement layer on your own cases.