Medicare drug coverage

Estradiol: 2027 Medicare Part D coverage

5,495 of 5,495 Part D plans (100%) list estradiol on their 2027 formulary, the same share as 2026. 4% of those require prior authorization, step therapy, or a quantity limit.

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2027 compared with 2026

Estradiol is number 181 by total Medicare Part D spending in 2024 ($218 million). Plans that list it most often put it on tier 1. Counts use 107 RxNorm products for this name.

estradiol Part D coverage, 2026 and 2027
Measure20262027Change
Part D plans in the file5,5185,495-23
Plans that list it5,517 (100%)5,495 (100%)no change
Prior authorization (of plans that list it)19 (0%)0 (0%)no change
Step therapy (of plans that list it)0 (0%)0 (0%)no change
Quantity limit (of plans that list it)470 (9%)199 (4%)-5 points
Any of the three (of plans that list it)470 (9%)199 (4%)-5 points
Not listed or restricted (of all plans)471 (9%)199 (4%)-5 points

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Formulary tier

estradiol formulary tier, 2026 and 2027
Tier2026 plans2027 plans
Tier 13,486 (63%)3,680 (67%)
Tier 21,757 (32%)1,778 (32%)
Tier 3107 (2%)37 (1%)
Tier 4167 (3%)0 (0%)

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Plan by plan, 2026 to 2027

4,380 plan ids are in both files. 54 of them (1%) added prior authorization, step therapy, or a quantity limit for estradiol, and 0 stopped listing it.

estradiol: plans in both 2026 and 2027
Plan by planPlans
Same plan id in both years4,380
Listed it in 2026, not in 20270 (0%)
Listed it in 2027, not in 20260 (0%)
Moved it to a higher tier81 (2%)
Added prior authorization0 (0%)
Added step therapy0 (0%)
Added a quantity limit54 (1%)
Added at least one of the three54 (1%)
Removed at least one of the three262 (6%)
Plan ids new in 20271,115
2026 plan ids not in the 2027 file1,138

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

States from most to least restrictive

Share of 2027 Part D plans offered in each state that leave estradiol off the formulary or list it with prior authorization, step therapy, or a quantity limit. New York ranks first at 21%, with 0% of its plans using prior authorization or step therapy; Wyoming ranks last at 0%. Ties break on the prior authorization or step therapy share.

States from most to least restrictive for estradiol, 2027
RankState2027 plansNot listed or restrictedPrior auth or step therapyChange from 2026
1New York21521%0%-6 points
2Alaska911%0%-11 points
3Michigan1838%0%-4 points
4New Jersey745%0%-2 points
5Tennessee1575%0%-4 points
6District of Columbia215%0%-3 points
7Iowa645%0%-11 points
8West Virginia704%0%-10 points
9Virginia1454%0%-2 points
10Wisconsin974%0%-5 points
11North Carolina1774%0%-3 points
12Indiana1404%0%-3 points
13Kansas844%0%-4 points
14Missouri1714%0%-6 points
15Arkansas863%0%-8 points
16Ohio1733%0%-14 points
17Arizona1483%0%-3 points
18Minnesota633%0%-19 points
19Alabama1153%0%-1 point
20Kentucky1232%0%-7 points
21Louisiana1262%0%-20 points
22Delaware432%0%-7 points
23California3972%0%-1 point
24Illinois1332%0%-6 points
25Idaho452%0%-4 points
26Florida5492%0%-1 point
27Massachusetts922%0%-1 point
28Maryland492%0%-7 points
29Nebraska512%0%-13 points
30Mississippi1052%0%-6 points
31Colorado1062%0%-3 points
32Utah532%0%-3 points
33Pennsylvania3242%0%-7 points
34New Mexico681%0%-1 point
35Georgia1511%0%-8 points
36Oklahoma811%0%-4 points
37Oregon921%0%-8 points
38Nevada1001%0%-3 points
39Texas4121%0%-5 points
40Connecticut540%0%-8 points
41Hawaii500%0%-6 points
42Maine520%0%-9 points
43Montana270%0%-6 points
44North Dakota260%0%-30 points
45New Hampshire250%0%-24 points
46Rhode Island290%0%-6 points
47South Carolina910%0%-9 points
48South Dakota300%0%-30 points
49Vermont140%0%-15 points
50Washington1140%0%-8 points
51Wyoming130%0%-11 points

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

By parent organization

164 parent organizations offer 2027 Part D plans. Humana Inc. has the most, 884, and 0% of them leave estradiol off or restrict it.

estradiol coverage by parent organization, 2027
Parent organization2027 plans ↑List itRestrict it (of listing)Not listed or restrictedChange from 2026Plans that added a restriction
AIDS Healthcare Foundation1100%100%100%no change0
Alameda Alliance for Health1100%100%100%no change0
AllCare Health, Inc.1100%100%100%no change0
AlohaCare1100%0%0%no change0
BCBS MN, MT, NE, ND, WY, Wellmark IA and SD1100%0%0%no change0
CareOregon, Inc.1100%0%0%no change0
Contra Costa Health Services1100%0%0%no change0
DLP Marquette Health Plan, LLC1100%0%0%-100 points0
Health Plan of San Mateo1100%100%100%no change0
IMPERIAL COUNTY LOCAL HEALTH AUTHORITY1100%0%0%no change0
INLAND EMPIRE HEALTH PLAN1100%100%100%+100 points1
Itasca County1100%0%0%no change0
Kern Health Systems (KHS)1100%0%0%no change0
Local Initiative Health Authority for LA County1100%0%0%-100 points0
Muscogee Creek Nation1100%0%0%new in 20270
Orange County Health Authority1100%100%100%no change0
SAN FRANCISCO HEALTH AUTHORITY1100%0%0%no change0
SAN JOAQUIN COUNTY HEALTH COMMISSION1100%0%0%no change0
SANTA BARBARA SAN LUIS OBISPO REGIONAL HEALTH AUTH1100%0%0%no change0
SANTA CLARA COUNTY HEALTH AUTHORITY1100%0%0%-100 points0
SANTA CRUZ MONTEREY MERCED SAN BENITO MARIPOSA MAN1100%0%0%no change0
Samaritan Health Services, Inc.1100%0%0%no change0
The Schroer Group, Inc.1100%100%100%no change0
Ventura County Medi-Cal Managed Care Commission1100%0%0%no change0
BayCare Health System, Inc.2100%0%0%no change0

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

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Near it by Part D spending

About this data

A plan here is one Part D plan as the CMS formulary files list it: contract, plan, and segment. That covers Medicare Advantage plans with drug coverage and stand-alone drug plans. A plan lists a drug when its formulary has a row for any RxNorm product of that name. When it has several, the row with the lowest tier is the one counted, and restricted means that row has prior authorization, step therapy, or a quantity limit.

A plan with no row for the drug counts as not listing it. That can be a product the file codes another way, so read a low count as a lookup result, not a coverage decision. A state counts every plan the CMS landscape file offers there. Parent organizations are named as CMS names them. The drug list is the top 200 by total Part D spending.

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page

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