Medicare drug coverage
Medicare Part D drug coverage, 2027
How 5,495 Part D plans (5,172 Medicare Advantage plans with drug coverage and 323 stand-alone drug plans) cover the 200 drugs with the most Part D spending in 2024, and what changed from 2026.
License. US government work, Public Domain Mark 1.0.
The drug list
Drugs are ranked by total Part D spending in 2024. 192 drugs match formulary rows in both 2026 and 2027. The highest share of 2027 plans leaving a drug off or restricting it is 100%, for Ozempic, where 100% of plans use prior authorization or step therapy.
Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page
Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page
Ranks 1 to 50 by Part D spending
- Eliquis100% of plans list it, 93% of those restrict it#1
- Ozempic100% of plans list it, 100% of those restrict it#2
- Jardiance100% of plans list it, 98% of those restrict it#3
- Mounjaro97% of plans list it, 100% of those restrict it#4
- Xarelto51% of plans list it, 95% of those restrict it#5
- Trulicity96% of plans list it, 100% of those restrict it#6
- Trelegy100% of plans list it, 98% of those restrict it#7
- Farxiga100% of plans list it, 98% of those restrict it#8
- Humira23% of plans list it, 100% of those restrict it#9
- RevlimidNo 2027 formulary match#10
- Entresto46% of plans list it, 71% of those restrict it#11
- Januvia17% of plans list it, 86% of those restrict it#12
- Biktarvy100% of plans list it, 55% of those restrict it#13
- Xtandi100% of plans list it, 98% of those restrict it#14
- Stelara2% of plans list it, 100% of those restrict it#15
- Vyndamax58% of plans list it, 97% of those restrict it#16
- Lenalidomide100% of plans list it, 98% of those restrict it#17
- Enbrel100% of plans list it, 98% of those restrict it#18
- Myrbetriq54% of plans list it, 55% of those restrict it#19
- Imbruvica100% of plans list it, 98% of those restrict it#20
- Pomalyst100% of plans list it, 98% of those restrict it#21
- Ofev100% of plans list it, 98% of those restrict it#22
- Jakafi100% of plans list it, 98% of those restrict it#23
- Ibrance100% of plans list it, 98% of those restrict it#24
- Linzess100% of plans list it, 98% of those restrict it#25
- Ingrezza35% of plans list it, 95% of those restrict it#26
- RybelsusNo 2027 formulary match#27
- Dupixent100% of plans list it, 100% of those restrict it#28
- Skyrizi98% of plans list it, 98% of those restrict it#29
- Brukinsa100% of plans list it, 98% of those restrict it#30
- Repatha94% of plans list it, 98% of those restrict it#31
- Calquence100% of plans list it, 98% of those restrict it#32
- Tagrisso100% of plans list it, 98% of those restrict it#33
- Creon97% of plans list it, 0% of those restrict it#34
- Erleada100% of plans list it, 98% of those restrict it#35
- Rinvoq100% of plans list it, 98% of those restrict it#36
- Breo100% of plans list it, 98% of those restrict it#37
- Restasis56% of plans list it, 69% of those restrict it#38
- Opsumit4% of plans list it, 100% of those restrict it#39
- Cabometyx100% of plans list it, 98% of those restrict it#40
- XIFAXAN100% of plans list it, 97% of those restrict it#41
- Vraylar100% of plans list it, 98% of those restrict it#42
- Tradjenta100% of plans list it, 97% of those restrict it#43
- Austedo100% of plans list it, 98% of those restrict it#44
- Verzenio100% of plans list it, 98% of those restrict it#45
- Otezla100% of plans list it, 98% of those restrict it#46
- Nubeqa100% of plans list it, 98% of those restrict it#47
- Tresiba29% of plans list it, 6% of those restrict it#48
- Gemtesa80% of plans list it, 74% of those restrict it#49
- Venclexta100% of plans list it, 98% of those restrict it#50
Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page
Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page
Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page
Ranks 51 to 100 by Part D spending
- Uptravi58% of plans list it, 97% of those restrict it#51
- Spiriva100% of plans list it, 97% of those restrict it#52
- Lenvima100% of plans list it, 98% of those restrict it#53
- Rexulti100% of plans list it, 98% of those restrict it#54
- Anoro74% of plans list it, 100% of those restrict it#55
- Cosentyx71% of plans list it, 97% of those restrict it#56
- Shingrix100% of plans list it, 73% of those restrict it#57
- Kisqali100% of plans list it, 98% of those restrict it#58
- Arexvy100% of plans list it, 66% of those restrict it#59
- Prolia21% of plans list it, 100% of those restrict it#60
- Epclusa11% of plans list it, 84% of those restrict it#61
- Atorvastatin100% of plans list it, 68% of those restrict it#62
- Tyvaso3% of plans list it, 35% of those restrict it#63
- Vascepa57% of plans list it, 11% of those restrict it#64
- Oxervate7% of plans list it, 100% of those restrict it#65
- Janumet100% of plans list it, 95% of those restrict it#66
- Lantus96% of plans list it, 16% of those restrict it#67
- Adempas100% of plans list it, 100% of those restrict it#68
- Abiraterone acetate100% of plans list it, 97% of those restrict it#69
- Brilinta1% of plans list it, 0% of those restrict it#70
- Promacta2% of plans list it, 100% of those restrict it#71
- Basaglar1% of plans list it, 55% of those restrict it#72
- Nuplazid100% of plans list it, 98% of those restrict it#73
- Lumigan70% of plans list it, 28% of those restrict it#74
- Tivicay100% of plans list it, 54% of those restrict it#75
- Nurtec81% of plans list it, 98% of those restrict it#76
- Tremfya85% of plans list it, 98% of those restrict it#77
- Symbicort35% of plans list it, 100% of those restrict it#78
- Zenpep95% of plans list it, 0% of those restrict it#79
- Lynparza100% of plans list it, 98% of those restrict it#80
- Xeljanz1% of plans list it, 100% of those restrict it#81
- Kesimpta86% of plans list it, 81% of those restrict it#82
- Gammagard37% of plans list it, 94% of those restrict it#83
- Orencia12% of plans list it, 85% of those restrict it#84
- Triumeq100% of plans list it, 56% of those restrict it#85
- Taltz3% of plans list it, 30% of those restrict it#86
- Toujeo90% of plans list it, 17% of those restrict it#87
- Albuterol sulfate91% of plans list it, 0% of those restrict it#88
- Genvoya100% of plans list it, 55% of those restrict it#89
- Descovy100% of plans list it, 62% of those restrict it#90
- Gabapentin100% of plans list it, 78% of those restrict it#91
- Dovato100% of plans list it, 51% of those restrict it#92
- Sprycel0% of plans list it, 74% of those restrict it#93
- Xiidra73% of plans list it, 75% of those restrict it#94
- Privigen39% of plans list it, 100% of those restrict it#95
- Orgovyx100% of plans list it, 98% of those restrict it#96
- Abrysvo100% of plans list it, 66% of those restrict it#97
- Levothyroxine sodium100% of plans list it, 0% of those restrict it#98
- Metoprolol succinate100% of plans list it, 0% of those restrict it#99
- Stiolto61% of plans list it, 96% of those restrict it#100
Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page
Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page
Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page
Ranks 101 to 150 by Part D spending
- Symtuza100% of plans list it, 51% of those restrict it#101
- Inlyta100% of plans list it, 98% of those restrict it#102
- Velphoro6% of plans list it, 12% of those restrict it#103
- Rosuvastatin calcium100% of plans list it, 69% of those restrict it#104
- Ubrelvy66% of plans list it, 97% of those restrict it#105
- Tasigna1% of plans list it, 100% of those restrict it#106
- Juluca100% of plans list it, 51% of those restrict it#107
- Multaq91% of plans list it, 65% of those restrict it#108
- Fluticasone / salmeterol96% of plans list it, 97% of those restrict it#109
- Kerendia100% of plans list it, 98% of those restrict it#110
- Octagam45% of plans list it, 100% of those restrict it#111
- Trintellix100% of plans list it, 98% of those restrict it#112
- Combivent100% of plans list it, 98% of those restrict it#113
- Incruse66% of plans list it, 99% of those restrict it#114
- Radicava38% of plans list it, 95% of those restrict it#115
- Odefsey100% of plans list it, 56% of those restrict it#116
- Omeprazole100% of plans list it, 32% of those restrict it#117
- Acthar2% of plans list it, 100% of those restrict it#118
- Gattex33% of plans list it, 100% of those restrict it#119
- Losartan potassium100% of plans list it, 83% of those restrict it#120
- Synthroid93% of plans list it, 0% of those restrict it#121
- StrensiqNo 2027 formulary match#122
- Diclofenac sodium100% of plans list it, 16% of those restrict it#123
- Korlym3% of plans list it, 100% of those restrict it#124
- Ojjaara100% of plans list it, 98% of those restrict it#125
- Praluent9% of plans list it, 100% of those restrict it#126
- Oxycontin1% of plans list it, 97% of those restrict it#127
- Humalog39% of plans list it, 16% of those restrict it#128
- Pantoprazole sodium100% of plans list it, 64% of those restrict it#129
- Synjardy51% of plans list it, 94% of those restrict it#130
- Advair65% of plans list it, 96% of those restrict it#131
- NovoLog83% of plans list it, 7% of those restrict it#132
- Nucala99% of plans list it, 100% of those restrict it#133
- Amlodipine besylate100% of plans list it, 0% of those restrict it#134
- Xolair100% of plans list it, 100% of those restrict it#135
- Duloxetine hydrochloride100% of plans list it, 95% of those restrict it#136
- Tamsulosin hydrochloride100% of plans list it, 41% of those restrict it#137
- Aimovig80% of plans list it, 100% of those restrict it#138
- Cyclosporine100% of plans list it, 84% of those restrict it#139
- VyndaqelNo 2027 formulary match#140
- Wegovy100% of plans list it, 100% of those restrict it#141
- Soliqua86% of plans list it, 98% of those restrict it#142
- Gammaplex24% of plans list it, 100% of those restrict it#143
- Potassium chloride100% of plans list it, 1% of those restrict it#144
- Camzyos7% of plans list it, 100% of those restrict it#145
- Fiasp79% of plans list it, 43% of those restrict it#146
- Ninlaro100% of plans list it, 98% of those restrict it#147
- Invokana6% of plans list it, 100% of those restrict it#148
- Rytary4% of plans list it, 64% of those restrict it#149
- Gammaked24% of plans list it, 92% of those restrict it#150
Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page
Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page
Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page
Ranks 151 to 200 by Part D spending
- Aristada92% of plans list it, 79% of those restrict it#151
- Caplyta100% of plans list it, 98% of those restrict it#152
- Forteo19% of plans list it, 89% of those restrict it#153
- Tibsovo100% of plans list it, 98% of those restrict it#154
- Cimzia4% of plans list it, 100% of those restrict it#155
- Qulipta62% of plans list it, 97% of those restrict it#156
- Orserdu100% of plans list it, 98% of those restrict it#157
- Emgality92% of plans list it, 100% of those restrict it#158
- Tymlos81% of plans list it, 100% of those restrict it#159
- Copaxone20% of plans list it, 100% of those restrict it#160
- Prezcobix100% of plans list it, 55% of those restrict it#161
- Premarin89% of plans list it, 7% of those restrict it#162
- Lisinopril100% of plans list it, 16% of those restrict it#163
- Budesonide / formoterol100% of plans list it, 98% of those restrict it#164
- Alecensa100% of plans list it, 98% of those restrict it#165
- Aripiprazole100% of plans list it, 69% of those restrict it#166
- Rezurock58% of plans list it, 97% of those restrict it#167
- VyvgartNo 2027 formulary match#168
- Humulin R96% of plans list it, 11% of those restrict it#169
- Lokelma97% of plans list it, 70% of those restrict it#170
- Actemra2% of plans list it, 100% of those restrict it#171
- Bosulif100% of plans list it, 98% of those restrict it#172
- UltomirisNo 2027 formulary match#173
- Xtampza17% of plans list it, 89% of those restrict it#174
- Fasenra93% of plans list it, 100% of those restrict it#175
- Orenitram36% of plans list it, 100% of those restrict it#176
- Lonsurf100% of plans list it, 98% of those restrict it#177
- Zejula100% of plans list it, 98% of those restrict it#178
- Takhzyro6% of plans list it, 64% of those restrict it#179
- Briviact15% of plans list it, 100% of those restrict it#180
- Estradiol100% of plans list it, 4% of those restrict it#181
- Benlysta100% of plans list it, 98% of those restrict it#182
- Teriparatide70% of plans list it, 97% of those restrict it#183
- KrystexxaNo 2027 formulary match#184
- Xywav2% of plans list it, 100% of those restrict it#185
- Ezetimibe100% of plans list it, 71% of those restrict it#186
- Epidiolex100% of plans list it, 98% of those restrict it#187
- Mekinist100% of plans list it, 98% of those restrict it#188
- Welireg100% of plans list it, 98% of those restrict it#189
- Mesalamine100% of plans list it, 61% of those restrict it#190
- Xigduo43% of plans list it, 99% of those restrict it#191
- Victoza0% of plans list it, 100% of those restrict it#192
- Dapagliflozin100% of plans list it, 97% of those restrict it#193
- Jaypirca100% of plans list it, 98% of those restrict it#194
- Arnuity91% of plans list it, 99% of those restrict it#195
- Buprenorphine / naloxone100% of plans list it, 44% of those restrict it#196
- Pregabalin100% of plans list it, 90% of those restrict it#197
- Vemlidy49% of plans list it, 78% of those restrict it#198
- Scemblix100% of plans list it, 98% of those restrict it#199
- HizentraNo 2027 formulary match#200
Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page
Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page
Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page
About this data
A plan here is one Part D plan as the CMS formulary files list it: contract, plan, and segment. That covers Medicare Advantage plans with drug coverage and stand-alone drug plans. A plan lists a drug when its formulary has a row for any RxNorm product of that name. When it has several, the row with the lowest tier is the one counted, and restricted means that row has prior authorization, step therapy, or a quantity limit.
A plan with no row for the drug counts as not listing it. That can be a product the file codes another way, so read a low count as a lookup result, not a coverage decision. A state counts every plan the CMS landscape file offers there. Parent organizations are named as CMS names them. The drug list is the top 200 by total Part D spending.
Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page
Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page
Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page