Medicare drug coverage

Orenitram: 2027 Medicare Part D coverage

1,983 of 5,495 Part D plans (36%) list Orenitram on their 2027 formulary, down 3 points from 2026. 100% of those require prior authorization, step therapy, or a quantity limit.

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2027 compared with 2026

Orenitram is number 176 by total Medicare Part D spending in 2024 ($230 million). Plans that list it most often put it on tier 4. Counts use 9 RxNorm products for this name.

Orenitram Part D coverage, 2026 and 2027
Measure20262027Change
Part D plans in the file5,5185,495-23
Plans that list it2,134 (39%)1,983 (36%)-3 points
Prior authorization (of plans that list it)2,134 (100%)1,983 (100%)no change
Step therapy (of plans that list it)0 (0%)0 (0%)no change
Quantity limit (of plans that list it)99 (5%)86 (4%)no change
Any of the three (of plans that list it)2,134 (100%)1,983 (100%)no change
Not listed or restricted (of all plans)5,518 (100%)5,495 (100%)no change

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Formulary tier

Orenitram formulary tier, 2026 and 2027
Tier2026 plans2027 plans
Tier 134 (2%)25 (1%)
Tier 21 (0%)0 (0%)
Tier 339 (2%)57 (3%)
Tier 42,060 (97%)1,901 (96%)

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Plan by plan, 2026 to 2027

4,380 plan ids are in both files. 0 of them (0%) added prior authorization, step therapy, or a quantity limit for Orenitram, and 9 stopped listing it.

Orenitram: plans in both 2026 and 2027
Plan by planPlans
Same plan id in both years4,380
Listed it in 2026, not in 20279 (0%)
Listed it in 2027, not in 202649 (1%)
Moved it to a higher tier2 (0%)
Added prior authorization0 (0%)
Added step therapy0 (0%)
Added a quantity limit0 (0%)
Added at least one of the three0 (0%)
Removed at least one of the three0 (0%)
Plan ids new in 20271,115
2026 plan ids not in the 2027 file1,138

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

States from most to least restrictive

Share of 2027 Part D plans offered in each state that leave Orenitram off the formulary or list it with prior authorization, step therapy, or a quantity limit. North Dakota ranks first at 100%, with 69% of its plans using prior authorization or step therapy; Hawaii ranks last at 100%. Ties break on the prior authorization or step therapy share.

States from most to least restrictive for Orenitram, 2027
RankState2027 plansNot listed or restrictedPrior auth or step therapyChange from 2026
1North Dakota26100%69%no change
2Minnesota63100%68%no change
3Massachusetts92100%66%no change
4Idaho45100%62%no change
5South Dakota30100%60%no change
6Michigan183100%60%no change
7Rhode Island29100%59%no change
8New Mexico68100%53%no change
9Wisconsin97100%46%no change
10Wyoming13100%46%no change
11Ohio173100%39%no change
12Nebraska51100%39%no change
13New Jersey74100%39%no change
14Texas412100%39%no change
15Virginia145100%39%no change
16North Carolina177100%38%no change
17District of Columbia21100%38%no change
18Iowa64100%38%no change
19Indiana140100%37%no change
20Nevada100100%37%no change
21Florida549100%36%no change
22New York215100%36%no change
23Arizona148100%36%no change
24South Carolina91100%35%no change
25Delaware43100%35%no change
26Maine52100%35%no change
27Utah53100%34%no change
28Alabama115100%34%no change
29Alaska9100%33%no change
30Pennsylvania324100%33%no change
31Kentucky123100%33%no change
32California397100%32%no change
33New Hampshire25100%32%no change
34Tennessee157100%32%no change
35Georgia151100%32%no change
36Colorado106100%31%no change
37Oklahoma81100%31%no change
38Washington114100%31%no change
39Connecticut54100%30%no change
40Montana27100%30%no change
41Mississippi105100%30%no change
42Kansas84100%29%no change
43Missouri171100%25%no change
44Arkansas86100%24%no change
45Illinois133100%24%no change
46Oregon92100%22%no change
47Louisiana126100%21%no change
48Vermont14100%21%no change
49West Virginia70100%21%no change
50Maryland49100%20%no change
51Hawaii50100%20%no change

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

By parent organization

164 parent organizations offer 2027 Part D plans. Humana Inc. has the most, 884, and 100% of them leave Orenitram off or restrict it.

Orenitram coverage by parent organization, 2027
Parent organization2027 plans ↓List itRestrict it (of listing)Not listed or restrictedChange from 2026Plans that added a restriction
Humana Inc.8840%none list it100%no change0
UnitedHealth Group, Inc.850100%100%100%no change0
Devoted Health, Inc.7280%none list it100%no change0
CVS Health Corporation6330%none list it100%no change0
Elevance Health, Inc.29492%100%100%no change0
Centene Corporation2680%none list it100%no change0
Health Care Service Corporation231100%100%100%no change0
Kaiser Foundation Health Plan, Inc.1120%none list it100%no change0
Highmark Health980%none list it100%no change0
SCAN Group850%none list it100%no change0
Alignment Healthcare USA, LLC77100%100%100%no change0
Guidewell Mutual Holding Corporation5569%100%100%no change0
Blue Cross Blue Shield of Michigan Mutual Ins. Co.43100%100%100%no change0
Molina Healthcare, Inc.430%none list it100%no change0
Corewell Health40100%100%100%no change0
Zing Health Consolidator, Inc360%none list it100%no change0
CAPITAL BLUE CROSS35100%100%100%no change0
Medica Holding Company3187%100%100%no change0
UPMC Health System30100%100%100%no change0
Universal Health Services, Inc.290%none list it100%no change0
MHH Healthcare, L.P.2677%100%100%no change0
Independence Health Group, Inc.2544%100%100%no change0
Point32Health, Inc.23100%100%100%no change0
BlueCross BlueShield of Tennessee220%none list it100%no change0
California Physicians' Service220%none list it100%no change0

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

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Near it by Part D spending

About this data

A plan here is one Part D plan as the CMS formulary files list it: contract, plan, and segment. That covers Medicare Advantage plans with drug coverage and stand-alone drug plans. A plan lists a drug when its formulary has a row for any RxNorm product of that name. When it has several, the row with the lowest tier is the one counted, and restricted means that row has prior authorization, step therapy, or a quantity limit.

A plan with no row for the drug counts as not listing it. That can be a product the file codes another way, so read a low count as a lookup result, not a coverage decision. A state counts every plan the CMS landscape file offers there. Parent organizations are named as CMS names them. The drug list is the top 200 by total Part D spending.

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page

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