Medicare drug coverage

Trintellix: 2027 Medicare Part D coverage

5,495 of 5,495 Part D plans (100%) list Trintellix on their 2027 formulary, the same share as 2026. 98% of those require prior authorization, step therapy, or a quantity limit.

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2027 compared with 2026

Trintellix is number 112 by total Medicare Part D spending in 2024 ($392 million). Plans that list it most often put it on tier 4. Counts use 4 RxNorm products for this name.

Trintellix Part D coverage, 2026 and 2027
Measure20262027Change
Part D plans in the file5,5185,495-23
Plans that list it5,517 (100%)5,495 (100%)no change
Prior authorization (of plans that list it)1,500 (27%)1,870 (34%)+7 points
Step therapy (of plans that list it)1,474 (27%)1,281 (23%)-3 points
Quantity limit (of plans that list it)5,184 (94%)5,298 (96%)+2 points
Any of the three (of plans that list it)5,298 (96%)5,390 (98%)+2 points
Not listed or restricted (of all plans)5,299 (96%)5,390 (98%)+2 points

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Formulary tier

Trintellix formulary tier, 2026 and 2027
Tier2026 plans2027 plans
Tier 1163 (3%)123 (2%)
Tier 210 (0%)1 (0%)
Tier 3703 (13%)1,224 (22%)
Tier 44,641 (84%)4,147 (75%)

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Plan by plan, 2026 to 2027

4,380 plan ids are in both files. 218 of them (5%) added prior authorization, step therapy, or a quantity limit for Trintellix, and 0 stopped listing it.

Trintellix: plans in both 2026 and 2027
Plan by planPlans
Same plan id in both years4,380
Listed it in 2026, not in 20270 (0%)
Listed it in 2027, not in 20260 (0%)
Moved it to a higher tier273 (6%)
Added prior authorization122 (3%)
Added step therapy8 (0%)
Added a quantity limit91 (2%)
Added at least one of the three218 (5%)
Removed at least one of the three124 (3%)
Plan ids new in 20271,115
2026 plan ids not in the 2027 file1,138

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

States from most to least restrictive

Share of 2027 Part D plans offered in each state that leave Trintellix off the formulary or list it with prior authorization, step therapy, or a quantity limit. Michigan ranks first at 100%, with 85% of its plans using prior authorization or step therapy; Maryland ranks last at 80%. Ties break on the prior authorization or step therapy share.

States from most to least restrictive for Trintellix, 2027
RankState2027 plansNot listed or restrictedPrior auth or step therapyChange from 2026
1Michigan183100%85%no change
2Alabama115100%80%no change
3Pennsylvania324100%75%no change
4Vermont14100%71%no change
5West Virginia70100%71%no change
6Arkansas86100%71%no change
7Illinois133100%68%no change
8South Carolina91100%68%no change
9Missouri171100%68%no change
10Kansas84100%67%no change
11Montana27100%67%+3 points
12Oklahoma81100%65%no change
13Utah53100%64%no change
14New Hampshire25100%64%no change
15Mississippi105100%64%no change
16Delaware43100%63%no change
17Tennessee157100%62%no change
18Wyoming13100%62%no change
19Connecticut54100%61%+4 points
20North Carolina177100%61%no change
21Louisiana126100%60%no change
22Kentucky123100%60%no change
23Florida549100%57%no change
24Indiana140100%56%no change
25Texas412100%56%+1 point
26Maine52100%56%no change
27Alaska9100%56%no change
28New Jersey74100%55%no change
29Iowa64100%55%no change
30Nebraska51100%53%no change
31New York215100%53%no change
32Arizona148100%51%+4 points
33New Mexico68100%49%+5 points
34Nevada100100%42%+4 points
35Rhode Island29100%38%no change
36South Dakota30100%37%no change
37Idaho45100%36%+4 points
38Minnesota63100%27%no change
39North Dakota26100%27%no change
40Wisconsin9799%46%no change
41Ohio17398%56%no change
42Washington11497%61%+1 point
43Virginia14596%59%no change
44Oregon9296%51%+8 points
45Georgia15195%65%no change
46Massachusetts9295%33%+24 points
47Colorado10690%62%+3 points
48Hawaii5088%66%+1 point
49California39788%24%+13 points
50District of Columbia2186%43%-2 points
51Maryland4980%63%-5 points

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

By parent organization

164 parent organizations offer 2027 Part D plans. Humana Inc. has the most, 884, and 100% of them leave Trintellix off or restrict it.

Trintellix coverage by parent organization, 2027
Parent organization2027 plans ↓List itRestrict it (of listing)Not listed or restrictedChange from 2026Plans that added a restriction
Humana Inc.884100%100%100%no change0
UnitedHealth Group, Inc.850100%100%100%no change0
Devoted Health, Inc.728100%100%100%no change0
CVS Health Corporation633100%100%100%no change0
Elevance Health, Inc.294100%100%100%no change0
Centene Corporation268100%100%100%no change0
Health Care Service Corporation231100%100%100%no change8
Kaiser Foundation Health Plan, Inc.112100%14%14%no change1
Highmark Health98100%100%100%no change15
SCAN Group85100%100%100%+100 points54
Alignment Healthcare USA, LLC77100%100%100%no change0
Guidewell Mutual Holding Corporation55100%100%100%no change0
Blue Cross Blue Shield of Michigan Mutual Ins. Co.43100%100%100%no change0
Molina Healthcare, Inc.43100%100%100%no change0
Corewell Health40100%100%100%no change0
Zing Health Consolidator, Inc36100%100%100%no change0
CAPITAL BLUE CROSS35100%100%100%no change0
Medica Holding Company31100%100%100%no change4
UPMC Health System30100%100%100%no change19
Universal Health Services, Inc.29100%100%100%no change0
MHH Healthcare, L.P.26100%100%100%no change0
Independence Health Group, Inc.25100%100%100%no change0
Point32Health, Inc.23100%100%100%+100 points19
BlueCross BlueShield of Tennessee22100%100%100%no change0
California Physicians' Service22100%100%100%no change0

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

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Near it by Part D spending

About this data

A plan here is one Part D plan as the CMS formulary files list it: contract, plan, and segment. That covers Medicare Advantage plans with drug coverage and stand-alone drug plans. A plan lists a drug when its formulary has a row for any RxNorm product of that name. When it has several, the row with the lowest tier is the one counted, and restricted means that row has prior authorization, step therapy, or a quantity limit.

A plan with no row for the drug counts as not listing it. That can be a product the file codes another way, so read a low count as a lookup result, not a coverage decision. A state counts every plan the CMS landscape file offers there. Parent organizations are named as CMS names them. The drug list is the top 200 by total Part D spending.

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page

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