Medicare drug coverage

Estradiol: 2027 Medicare Part D coverage

5,495 of 5,495 Part D plans (100%) list estradiol on their 2027 formulary, the plan's list of covered drugs (the same share as 2026). 4% of those require prior authorization, step therapy, or a quantity limit. Plan counts include both Medicare Advantage plans with drug coverage (5,172 MA-PD) and stand-alone drug plans (323 PDP).

License: a US government work, in the public domain (Public Domain Mark 1.0).

Data only, not plan advice. Confirm on Medicare.gov Plan Finder or 1-800-MEDICARE.

2027 compared with 2026

Estradiol is number 181 by total Medicare Part D spending in 2024 ($218 million). Plans that list it most often put it on tier 1 (a tier is the cost level a plan puts a drug on; a lower tier usually costs less). Counts use 107 RxNorm products for this name.

Estradiol Part D coverage, 2026 and 2027
Measure20262027Change
Part D plans in the file5,5185,495-23
Plans that list it5,517 (100%)5,495 (100%)no change
Prior authorization (of plans that list it)19 (0%)0 (0%)no change
Step therapy (of plans that list it)0 (0%)0 (0%)no change
Quantity limit (of plans that list it)470 (9%)199 (4%)-5 points
Any of the three (of plans that list it)470 (9%)199 (4%)-5 points
Not listed or restricted (of all plans)471 (9%)199 (4%)-5 points

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

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Formulary tier

Estradiol formulary tier, 2026 and 2027
Tier2026 plans2027 plans
Tier 13,486 (63%)3,680 (67%)
Tier 21,757 (32%)1,778 (32%)
Tier 3107 (2%)37 (1%)
Tier 4167 (3%)0 (0%)

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Plan by plan, 2026 to 2027

4,380 plan IDs are in both files. 54 of them (1%) added prior authorization, step therapy, or a quantity limit for estradiol, and 0 stopped listing it.

Estradiol: plans in both 2026 and 2027
Plan by planPlans
Same plan ID in both years4,380
Listed it in 2026, not in 20270 (0%)
Listed it in 2027, not in 20260 (0%)
Moved it to a higher tier81 (2%)
Added prior authorization0 (0%)
Added step therapy0 (0%)
Added a quantity limit54 (1%)
Added at least one of the three54 (1%)
Removed at least one of the three262 (6%)
Plan IDs new in 20271,115
2026 plan IDs not in the 2027 file1,138

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

States from most to least restrictive

Share of 2027 Part D plans offered in each state that leave estradiol off the formulary or list it with prior authorization, step therapy, or a quantity limit. New York ranks first at 21%, with 0% of its plans using prior authorization or step therapy; 12 states tie for the lowest, 0%. States at the same share are marked Tied and share a rank.

States from most to least restrictive for Estradiol, 2027
RankState2027 plansNot listed or restrictedPrior auth or step therapyChange from 2026
1New York21521%0%-7 points
2Alaska911%0%-11 points
3Michigan1838%0%-4 points
Tied 4New Jersey745%0%-2 points
Tied 4Tennessee1575%0%-5 points
Tied 4District of Columbia215%0%-3 points
Tied 4Iowa645%0%-10 points
Tied 8West Virginia704%0%-10 points
Tied 8Virginia1454%0%-3 points
Tied 8Wisconsin974%0%-5 points
Tied 8North Carolina1774%0%-3 points
Tied 8Indiana1404%0%-2 points
Tied 8Kansas844%0%-4 points
Tied 8Missouri1714%0%-6 points
Tied 15Arkansas863%0%-9 points
Tied 15Ohio1733%0%-15 points
Tied 15Arizona1483%0%-3 points
Tied 15Minnesota633%0%-20 points
Tied 15Alabama1153%0%-1 point
Tied 20Kentucky1232%0%-8 points
Tied 20Louisiana1262%0%-20 points
Tied 20Delaware432%0%-8 points
Tied 20California3972%0%-1 point
Tied 20Illinois1332%0%-7 points
Tied 20Idaho452%0%-4 points
Tied 20Florida5492%0%-2 points
Tied 20Massachusetts922%0%-1 point
Tied 20Maryland492%0%-8 points
Tied 20Nebraska512%0%-13 points
Tied 20Mississippi1052%0%-6 points
Tied 20Colorado1062%0%-3 points
Tied 20Utah532%0%-3 points
Tied 20Pennsylvania3242%0%-6 points
Tied 34New Mexico681%0%-2 points
Tied 34Georgia1511%0%-9 points
Tied 34Oklahoma811%0%-4 points
Tied 34Oregon921%0%-8 points
Tied 34Nevada1001%0%-3 points
Tied 34Texas4121%0%-5 points
Tied 40Connecticut540%0%-8 points
Tied 40Hawaii500%0%-6 points
Tied 40Maine520%0%-9 points
Tied 40Montana270%0%-6 points
Tied 40North Dakota260%0%-30 points
Tied 40New Hampshire250%0%-24 points
Tied 40Rhode Island290%0%-6 points
Tied 40South Carolina910%0%-9 points
Tied 40South Dakota300%0%-30 points
Tied 40Vermont140%0%-15 points
Tied 40Washington1140%0%-8 points
Tied 40Wyoming130%0%-11 points

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

By parent organization

164 parent organizations offer 2027 Part D plans. Humana Inc. has the most, 884, and 0% of them leave estradiol off or restrict it.

Estradiol coverage by parent organization, 2027
Parent organization2027 plans ↑List itRestrict it (of listing)Not listed or restrictedChange from 2026Plans that added a restriction
BrightSpring Health Services, Inc.2100%100%100%no change0
Community Health Group2100%0%0%no change0
Community Health Plan of Washington2100%0%0%-100 points0
Denver Health and Hospital Authority2100%0%0%-50 points0
Elevance Health, Inc. & BCBSMA & BCBSRI & BCBSVT2100%0%0%no change0
Elite Health Systems, Inc.2100%0%0%no change0
Group Health Cooperative of Eau Claire2100%0%0%-100 points0
Hamaspik of Rockland County, Inc.2100%100%100%+100 points2
ISNP Holdings, LLC2100%0%0%-50 points0
Kansas Superior Select2100%100%100%no change0
Missouri Healthcare Advisors, LLC2100%0%0%-50 points0
MultiCare Health Systems2100%0%0%new in 20270
NEIGHBORHOOD HEALTH PLAN OF RHODE ISLAND2100%0%0%no change0
PrimeWest Rural MN Health Care Access Initiative2100%100%100%no change0
Regency ISNP Holdings LLC2100%100%100%no change0
Select Founders, LLC2100%100%100%no change0
Sentara Health Care (SHC)2100%0%0%-100 points0
South Country Health Alliance2100%0%0%-100 points0
The Regents of the University of California2100%0%0%no change0
Troy Holdings, Inc.2100%0%0%no change0
Associated Care Ventures, Inc.3100%67%67%no change0
Aultman Health Foundation3100%0%0%no change0
Banner Health3100%67%67%-33 points0
Bexar County Hospital District3100%0%0%no change0
Blue Cross Blue Shield of Nebraska3100%0%0%no change0

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Near it by Part D spending

About this data

A plan here is one Part D plan as the CMS formulary files list it: contract, plan, and segment. That covers Medicare Advantage plans with drug coverage and stand-alone drug plans. A plan lists a drug when its formulary has a row for any RxNorm product of that name. When it has several, the row with the lowest tier is the one counted, and restricted means that row has prior authorization, step therapy, or a quantity limit.

A plan with no row for the drug counts as not listing it. That can be a product the file codes another way, so read a low count as a lookup result, not a coverage decision. A state counts every plan the CMS landscape file offers there. Parent organizations are named as CMS names them. The drug list is the top 200 by total Part D spending.

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page

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