Is Epclusa a Controlled Substance? No

No. Epclusa (velpatasvir and sofosbuvir) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and velpatasvir and sofosbuvir is not on the DEA controlled substances list.

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Schedule check

Schedule sources for Epclusa
Source	What it lists
FDA NDC directory	4 prescription listings from 1 labelers, none with a DEA schedule
DEA controlled substances list	velpatasvir and sofosbuvir is not on the list

Epclusa NDC listings

NDC listings for Epclusa
NDC	Product	Form	Strength	Labeler	DEA schedule
61958-2205	Epclusa	pellet	37.5 mg/1; 150 mg/1	Gilead Sciences, Inc.	None
61958-2204	Epclusa	pellet	50 mg/1; 200 mg/1	Gilead Sciences, Inc.	None
61958-2201	Epclusa	tablet, film coated	100 mg/1; 400 mg/1	Gilead Sciences, Inc.	None
61958-2203	Epclusa	tablet, film coated	50 mg/1; 200 mg/1	Gilead Sciences, Inc.	None

Questions

Is Epclusa a controlled substance?

No. Epclusa (velpatasvir and sofosbuvir) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and velpatasvir and sofosbuvir is not on the DEA controlled substances list.

Is Epclusa a narcotic?

No. Epclusa (velpatasvir and sofosbuvir) is not on the DEA controlled substances list, so the DEA does not classify it as a narcotic. Its FDA established pharmacologic class is Hepatitis C Virus NS5A Inhibitor and Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor.

Does this page cover state schedules?

No. This page reports the federal schedule only. Some states schedule drugs on their own; check your state board of pharmacy.