FDA drug class
Aldosterone Antagonists list
Every FDA-approved prescription drug the FDA NDC directory tags with the Aldosterone Antagonist [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 2 single-ingredient drugs in this class: eplerenone, spironolactone. Another 1 combination product include one of them.
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Aldosterone Antagonists (3)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Eplerenone | Inspra | Single ingredient | 21 | Not controlled |
| Spironolactone | Aldactone | Single ingredient | 183 | Not controlled |
| Spironolactone and hydrochlorothiazide | None listed | Combination | 12 | Not controlled |
FDA established pharmacologic class: Aldosterone Antagonist [EPC].
Questions
What drugs are Aldosterone Antagonists?
The FDA NDC directory lists 2 single-ingredient drugs in this class: eplerenone, spironolactone. Another 1 combination product include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.