FDA drug class

Amide Local Anesthetics list

Every FDA-approved prescription drug the FDA NDC directory tags with the Amide Local Anesthetic [EPC] class, with brand names and DEA schedules.

Source: FDA NDC Directory file dated 2026-10-22. Publisher page

The FDA NDC directory lists 5 single-ingredient drugs in this class: bupivacaine, lidocaine, mepivacaine, prilocaine, ropivacaine. Another 8 combination products include one of them.

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Amide Local Anesthetics (13)

Amide Local Anesthetics: FDA Amide Local Anesthetic class
DrugBrand namesTypeNDC listingsDEA schedule
BupivacaineMarcaine, Sensorcaine, ExparelSingle ingredient115Not controlled
LidocaineZtlido, Lidoderm, Xylocaine, AktenSingle ingredient383Not controlled
MepivacaineCarbocaineSingle ingredient19Not controlled
PrilocaineCitanest PlainSingle ingredient1Not controlled
RopivacaineNaropinSingle ingredient79Not controlled
Articaine and epinephrineOrablocCombination28Not controlled
Bupivacaine and epinephrineVivacaine, Marcaine with EpinephrineCombination27Not controlled
Bupivacaine and meloxicamZynrelefCombination2Not controlled
Lidocaine and dextroseNone listedCombination3Not controlled
Lidocaine and epinephrineFlavaltaCombination60Not controlled
Lidocaine and prilocaineOraqixCombination18Not controlled
Lidocaine and tetracainePliaglisCombination1Not controlled
Prilocaine and epinephrineCitanest Forte DENTALCombination2Not controlled

FDA established pharmacologic class: Amide Local Anesthetic [EPC].

Questions

What drugs are Amide Local Anesthetics?

The FDA NDC directory lists 5 single-ingredient drugs in this class: bupivacaine, lidocaine, mepivacaine, prilocaine, ropivacaine. Another 8 combination products include one of them.

Where does this list come from?

From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.

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