FDA drug class
Atypical Antipsychotics list
Every FDA-approved prescription drug the FDA NDC directory tags with the Atypical Antipsychotic [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 16 single-ingredient drugs in this class: aripiprazole, aripiprazole lauroxil, asenapine, brexpiprazole, cariprazine, clozapine, iloperidone, lumateperone, and more. Another 2 combination products include one of them.
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Atypical Antipsychotics (18)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Aripiprazole | Abilify Asimtufii, Abilify, Opipza | Single ingredient | 269 | Not controlled |
| Aripiprazole lauroxil | Aristada | Single ingredient | 5 | Not controlled |
| Asenapine | Saphris, Secuado | Single ingredient | 24 | Not controlled |
| Brexpiprazole | Rexulti | Single ingredient | 14 | Not controlled |
| Cariprazine | Vraylar | Single ingredient | 6 | Not controlled |
| Clozapine | Clozaril, Versacloz | Single ingredient | 48 | Not controlled |
| Iloperidone | Fanapt | Single ingredient | 18 | Not controlled |
| Lumateperone | Caplyta | Single ingredient | 3 | Not controlled |
| Lurasidone | Latuda | Single ingredient | 136 | Not controlled |
| Olanzapine | Zyprexa | Single ingredient | 219 | Not controlled |
| Paliperidone | Invega | Single ingredient | 69 | Not controlled |
| Paliperidone palmitate | Invega Sustenna, Invega Trinza, Invega Hafyera | Single ingredient | 17 | Not controlled |
| Pimavanserin | Nuplazid | Single ingredient | 3 | Not controlled |
| Quetiapine | Seroquel | Single ingredient | 349 | Not controlled |
| Risperidone | Uzedy, Risperdal | Single ingredient | 176 | Not controlled |
| Ziprasidone | Geodon | Single ingredient | 84 | Not controlled |
| Olanzapine and fluoxetine | None listed | Combination | 15 | Not controlled |
| Olanzapine and samidorphan l-malate | Lybalvi | Combination | 4 | Not controlled |
FDA established pharmacologic class: Atypical Antipsychotic [EPC].
Questions
What drugs are Atypical Antipsychotics?
The FDA NDC directory lists 16 single-ingredient drugs in this class: aripiprazole, aripiprazole lauroxil, asenapine, brexpiprazole, cariprazine, clozapine, iloperidone, lumateperone, and more. Another 2 combination products include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
- AripiprazoleAbilify Asimtufii, Abilify
- Aripiprazole lauroxilAristada
- AsenapineSaphris, Secuado
- BrexpiprazoleRexulti
- CariprazineVraylar
- ClozapineClozaril, Versacloz
- IloperidoneFanapt
- LumateperoneCaplyta
- All drug classesFDA EPC
- Controlled substances by scheduleDEA list
- Generic drug lookupFDA Orange Book
- NDC lookupFDA NDC directory
- Medicare Part D drug coverageBy plan and state