FDA drug class
Central alpha-2 Adrenergic Agonists list
Every FDA-approved prescription drug the FDA NDC directory tags with the Central alpha-2 Adrenergic Agonist [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 5 single-ingredient drugs in this class: clonidine, dexmedetomidine, guanfacine, methyldopa, tizanidine.
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Central alpha-2 Adrenergic Agonists (5)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Clonidine | Javadin, Onyda XR, Qlonilik, Duraclon | Single ingredient | 174 | Not controlled |
| Dexmedetomidine | Igalmi, Precedex | Single ingredient | 82 | Not controlled |
| Guanfacine | Intuniv | Single ingredient | 123 | Not controlled |
| Methyldopa | None listed | Single ingredient | 4 | Not controlled |
| Tizanidine | Zanaflex, Ontralfy | Single ingredient | 200 | Not controlled |
FDA established pharmacologic class: Central alpha-2 Adrenergic Agonist [EPC].
Questions
What drugs are Central alpha-2 Adrenergic Agonists?
The FDA NDC directory lists 5 single-ingredient drugs in this class: clonidine, dexmedetomidine, guanfacine, methyldopa, tizanidine.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.