FDA drug class

Estrogen Agonist/Antagonists list

Every FDA-approved prescription drug the FDA NDC directory tags with the Estrogen Agonist/Antagonist [EPC] class, with brand names and DEA schedules.

Source: FDA NDC Directory file dated 2026-10-22. Publisher page

The FDA NDC directory lists 5 single-ingredient drugs in this class: clomiphene, ospemifene, raloxifene, tamoxifen, toremifene. Another 1 combination product include one of them.

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Estrogen Agonist/Antagonists (6)

Estrogen Agonist/Antagonists: FDA Estrogen Agonist/Antagonist class
DrugBrand namesTypeNDC listingsDEA schedule
ClomipheneClomidSingle ingredient11Not controlled
OspemifeneOsphenaSingle ingredient1Not controlled
RaloxifeneEvistaSingle ingredient22Not controlled
TamoxifenSoltamoxSingle ingredient18Not controlled
ToremifeneFarestonSingle ingredient3Not controlled
Estrogens conjugated and bazedoxifene acetateDuaveeCombination2Not controlled

FDA established pharmacologic class: Estrogen Agonist/Antagonist [EPC].

Questions

What drugs are Estrogen Agonist/Antagonists?

The FDA NDC directory lists 5 single-ingredient drugs in this class: clomiphene, ospemifene, raloxifene, tamoxifen, toremifene. Another 1 combination product include one of them.

Where does this list come from?

From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.

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