FDA drug class

Proton Pump Inhibitors list

Every FDA-approved prescription drug the FDA NDC directory tags with the Proton Pump Inhibitor [EPC] class, with brand names and DEA schedules.

Source: FDA NDC Directory file dated 2026-10-22. Publisher page

The FDA NDC directory lists 7 single-ingredient drugs in this class: dexlansoprazole, esomeprazole, esomeprazole strontium, lansoprazole, omeprazole, pantoprazole, rabeprazole. Another 3 combination products include one of them.

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Proton Pump Inhibitors (10)

Proton Pump Inhibitors: FDA Proton Pump Inhibitor class
DrugBrand namesTypeNDC listingsDEA schedule
DexlansoprazoleDexilantSingle ingredient22Not controlled
EsomeprazoleNexiumSingle ingredient127Not controlled
Esomeprazole strontiumNone listedSingle ingredient2Not controlled
LansoprazolePrevacidSingle ingredient81Not controlled
OmeprazolePrilosecSingle ingredient176Not controlled
PantoprazoleProtonixSingle ingredient167Not controlled
RabeprazoleAciphexSingle ingredient38Not controlled
Naproxen and esomeprazoleNone listedCombination21Not controlled
Omeprazole and sodium bicarbonateZegeridCombination21Not controlled
Omeprazole, amoxicillin and rifabutinTaliciaCombination1Not controlled

FDA established pharmacologic class: Proton Pump Inhibitor [EPC].

Questions

What drugs are Proton Pump Inhibitors?

The FDA NDC directory lists 7 single-ingredient drugs in this class: dexlansoprazole, esomeprazole, esomeprazole strontium, lansoprazole, omeprazole, pantoprazole, rabeprazole. Another 3 combination products include one of them.

Where does this list come from?

From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.

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