FDA drug class
Small Interfering RNAs list
Every FDA-approved prescription drug the FDA NDC directory tags with the Small Interfering RNA [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 5 single-ingredient drugs in this class: fitusiran, givosiran, patisiran, plozasiran, vutrisiran.
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Small Interfering RNAs (5)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Fitusiran | Qfitlia | Single ingredient | 2 | Not controlled |
| Givosiran | Givlaari | Single ingredient | 1 | Not controlled |
| Patisiran | Onpattro | Single ingredient | 1 | Not controlled |
| Plozasiran | Redemplo | Single ingredient | 1 | Not controlled |
| Vutrisiran | Amvuttra | Single ingredient | 1 | Not controlled |
FDA established pharmacologic class: Small Interfering RNA [EPC].
Questions
What drugs are Small Interfering RNAs?
The FDA NDC directory lists 5 single-ingredient drugs in this class: fitusiran, givosiran, patisiran, plozasiran, vutrisiran.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.