FDA drug class

Thiazide-like Diuretics list

Every FDA-approved prescription drug the FDA NDC directory tags with the Thiazide-like Diuretic [EPC] class, with brand names and DEA schedules.

Source: FDA NDC Directory file dated 2026-10-22. Publisher page

The FDA NDC directory lists 3 single-ingredient drugs in this class: chlorthalidone, indapamide, metolazone. Another 3 combination products include one of them.

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Thiazide-like Diuretics (6)

Thiazide-like Diuretics: FDA Thiazide-like Diuretic class
DrugBrand namesTypeNDC listingsDEA schedule
ChlorthalidoneThalitone, HemiclorSingle ingredient105Not controlled
IndapamideNone listedSingle ingredient17Not controlled
MetolazoneNone listedSingle ingredient62Not controlled
Atenolol and chlorthalidoneNone listedCombination17Not controlled
Azilsartan kamedoxomil and chlorthalidoneEdarbyclorCombination2Not controlled
Telmisartan, amlodipine and indapamideWidaplikCombination3Not controlled

FDA established pharmacologic class: Thiazide-like Diuretic [EPC].

Questions

What drugs are Thiazide-like Diuretics?

The FDA NDC directory lists 3 single-ingredient drugs in this class: chlorthalidone, indapamide, metolazone. Another 3 combination products include one of them.

Where does this list come from?

From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.

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