Medicare drug coverage

Mesalamine: 2027 Medicare Part D coverage

5,495 of 5,495 Part D plans (100%) list mesalamine on their 2027 formulary, the plan's list of covered drugs (the same share as 2026). 61% of those require prior authorization, step therapy, or a quantity limit. Plan counts include both Medicare Advantage plans with drug coverage (5,172 MA-PD) and stand-alone drug plans (323 PDP).

License: a US government work, in the public domain (Public Domain Mark 1.0).

Data only, not plan advice. Confirm on Medicare.gov Plan Finder or 1-800-MEDICARE.

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2027 compared with 2026

Mesalamine is number 190 by total Medicare Part D spending in 2024 ($204 million). Plans that list it most often put it on tier 4 (a tier is the cost level a plan puts a drug on; a lower tier usually costs less). Counts use 18 RxNorm products for this name.

Mesalamine Part D coverage, 2026 and 2027
Measure20262027Change
Part D plans in the file5,5185,495-23
Plans that list it5,517 (>99%)5,495 (100%)no change
Prior authorization (of plans that list it)0 (0%)0 (0%)no change
Step therapy (of plans that list it)0 (0%)0 (0%)no change
Quantity limit (of plans that list it)2,955 (54%)3,341 (61%)+7 points
Any of the three (of plans that list it)2,955 (54%)3,341 (61%)+7 points
Not listed or restricted (of all plans)2,956 (54%)3,341 (61%)+7 points

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Every 2027 stand-alone drug plan

Each stand-alone Part D plan (PDP) with mesalamine's 2027 tier and limits. CMS files a PDP once per region, so one plan name can have several plan IDs; the row shows the tier and limits most of them use. Medicare Advantage drug plans are local: pick a state for its plan-by-plan table.

Mesalamine on every 2027 stand-alone Part D plan
Plan (PDP)Plan IDs2027 tier2027 limits
AARP Medicare Rx Preferred from UHC (PDP)39Tier 3QL
AARP Medicare Rx Saver from UHC (PDP)34Tier 4QL
Blue Medicare Rx Enhanced (PDP)1Tier 4QL
Blue Medicare Rx Standard (PDP)1Tier 4QL
Blue MedicareRx Essentials (PDP)1Tier 4None
Blue MedicareRx Plus (PDP)1Tier 4QL
Blue MedicareRx Premier (PDP)1Tier 4QL
Blue MedicareRx Value (PDP)1Tier 4None
Blue MedicareRx Value Plus (PDP)1Tier 4QL
Blue Shield Rx Enhanced (PDP)1Tier 3QL
Blue Shield Rx Plus (PDP)1Tier 3QL
BlueMedicare Complete Rx (PDP)1Tier 4None
BlueMedicare Premier Rx (PDP)2Tier 4QL (1 of 2 IDs)
BlueMedicare Value Rx (PDP)1Tier 4QL
BlueRx Enhanced Plus (PDP)1Tier 4None
BlueRx Essential (PDP)1Tier 4None
HealthSpring Assurance Rx (PDP)35Tier 4None
HealthSpring Extra Rx (PDP)2Tier 4None
HealthSpring Extra RX (PDP)3Tier 4None
Horizon Medicare Blue Rx Enhanced (PDP)1Tier 4QL
Horizon Medicare Blue Rx Standard (PDP)1Tier 4None
Humana Basic Rx Plan (PDP)34Tier 4QL
Humana Premier Rx Plan (PDP)34Tier 4QL
Humana Value Rx Plan (PDP)34Tier 4QL
MedicareBlue Rx Standard (PDP)1Tier 4None
Prescription Blue Premium (PDP)1Tier 4QL
Prescription Blue Select (PDP)1Tier 4QL
SilverScript Choice (PDP)20Tier 4None
Wellcare Classic (PDP)34Tier 3None
Wellcare Value Script (PDP)34Tier 1None

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

By dosage form

The 2027 formularies list mesalamine by dosage form. A plan can cover one form and leave off or restrict another, so each form is counted on its own, across all 5,495 plans.

Mesalamine by dosage form, 2027
Dosage formPlans that list itRestricted (of listing)Most common tier
Delayed release oral capsule2,968 (54%)1,462 (49%)Tier 4
Delayed release oral tablet4,304 (78%)2,645 (61%)Tier 4
Enema5,451 (99%)3,061 (56%)Tier 4
Extended release oral capsule4,834 (88%)3,448 (71%)Tier 4
Rectal suppository4,994 (91%)2,836 (57%)Tier 4

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Formulary tier

Mesalamine formulary tier, 2026 and 2027
Tier2026 plans2027 plans
Tier 1214 (4%)417 (8%)
Tier 21,299 (24%)1,094 (20%)
Tier 31,429 (26%)1,169 (21%)
Tier 42,575 (47%)2,815 (51%)

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Plan by plan, 2026 to 2027

4,380 plan IDs are in both files. 157 of them (4%) added prior authorization, step therapy, or a quantity limit for mesalamine, and 0 stopped listing it.

Mesalamine: plans in both 2026 and 2027
Plan by planPlans
Same plan ID in both years4,380
Listed it in 2026, not in 20270 (0%)
Listed it in 2027, not in 20260 (0%)
Moved it to a higher tier326 (7%)
Added prior authorization0 (0%)
Added step therapy0 (0%)
Added a quantity limit157 (4%)
Added at least one of the three157 (4%)
Removed at least one of the three29 (1%)
Plan IDs new in 20271,115
2026 plan IDs not in the 2027 file1,138

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

States from most to least restrictive

Share of 2027 Part D plans offered in each state that leave mesalamine off the formulary or list it with prior authorization, step therapy, or a quantity limit. New Hampshire ranks first at 88%, with 0% of its plans using prior authorization or step therapy; Minnesota ranks last at 35%. States at the same share are marked Tied and share a rank.

States from most to least restrictive for Mesalamine, 2027
RankState2027 plansNot listed or restrictedPrior auth or step therapyChange from 2026
1New Hampshire2588%0%+24 points
2New Mexico6887%0%+13 points
3Hawaii5082%0%+7 points
4Vermont1479%0%+10 points
5Montana2778%0%+6 points
6Utah5377%0%+8 points
7Oklahoma8175%0%-4 points
8North Carolina17773%0%+9 points
9Arizona14871%0%+16 points
Tied 10Alabama11570%0%+5 points
Tied 10Iowa6470%0%+16 points
Tied 10Virginia14570%0%+2 points
Tied 13Washington11469%0%+11 points
Tied 13Wyoming1369%0%+1 point
Tied 13Louisiana12669%0%+11 points
Tied 13Idaho4569%0%-5 points
Tied 17Oregon9268%0%+24 points
Tied 17Pennsylvania32468%0%+5 points
Tied 19Maine5267%0%+4 points
Tied 19West Virginia7067%0%-1 point
Tied 19Wisconsin9767%0%+16 points
Tied 22Maryland4965%0%+16 points
Tied 22Delaware4365%0%+8 points
Tied 22Indiana14065%0%+2 points
Tied 22Illinois13365%0%+5 points
26South Carolina9164%0%+11 points
Tied 27Kentucky12363%0%-1 point
Tied 27Nebraska5163%0%+8 points
Tied 29Florida54962%0%+8 points
Tied 29Colorado10662%0%+3 points
Tied 29Rhode Island2962%0%+1 point
32Kansas8461%0%+1 point
Tied 33Tennessee15760%0%+8 points
Tied 33Texas41260%0%+2 points
Tied 33Missouri17160%0%+5 points
36Mississippi10558%0%+2 points
Tied 37District of Columbia2157%0%+5 points
Tied 37Arkansas8657%0%-1 point
Tied 37Michigan18357%0%+3 points
Tied 40California39756%0%+14 points
Tied 40Alaska956%0%no change
Tied 40Connecticut5456%0%+11 points
Tied 43New Jersey7454%0%+13 points
Tied 43Ohio17354%0%+2 points
Tied 43Georgia15154%0%+8 points
Tied 46Massachusetts9250%0%+6 points
Tied 46North Dakota2650%0%+14 points
48Nevada10049%0%+8 points
49New York21547%0%+7 points
50South Dakota3037%0%+7 points
51Minnesota6335%0%-1 point

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

By parent organization

164 parent organizations offer 2027 Part D plans. Humana Inc. has the most, 884, and 100% of them leave mesalamine off or restrict it.

Mesalamine coverage by parent organization, 2027
Parent organization2027 plans ↑List itRestrict it (of listing)Not listed or restrictedChange from 2026Plans that added a restriction
CareFirst, Inc.5100%100%100%no change0
General Catalyst Group Management Holdings LP5100%0%0%new in 20270
Harris County Hospital District5100%100%100%no change0
Independent Living Systems, LLC5100%0%0%-100 points0
Mass General Brigham Incorporated5100%100%100%+100 points3
PacificSource5100%100%100%+100 points3
SNP Holdings, LLC5100%100%100%+100 points3
USAble Mutual Insurance Company5100%100%100%no change0
Baystate Health, Inc.6100%100%100%+100 points4
Blue Cross Blue Shield of Arizona6100%100%100%+75 points3
Blue Cross Blue Shield of Kansas6100%67%67%-4 points0
BlueCross BlueShield of South Carolina (BCBSSC)6100%100%100%+100 points6
CareSource6100%33%33%+4 points0
Clever Care Health Plan, Inc.6100%100%100%no change0
Eternal Health of Delaware, Inc.6100%100%100%+100 points5
Hawaii Medical Service Association6100%100%100%no change0
Health First Shared Services, Inc.6100%100%100%no change0
Independent Health Association, Inc.6100%0%0%no change0
LifeBridge Health, Inc.6100%100%100%+100 points6
The Health Plan of West Virginia, Inc.6100%0%0%no change0
UNICO Services, Inc.6100%100%100%no change0
Verda Healthcare, Inc.6100%0%0%-100 points0
Allina Health and Aetna Insurance Holding Company7100%0%0%no change0
Baylor Scott & White Health7100%100%100%no change0
Blue Cross and Blue Shield of Massachusetts, Inc.7100%100%100%no change0

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Near it by Part D spending

About this data

A plan here is one Part D plan as the CMS formulary files list it: contract, plan, and segment. That covers Medicare Advantage plans with drug coverage and stand-alone drug plans. A plan lists a drug when its formulary has a row for any RxNorm product of that name. When it has several, the row with the lowest tier is the one counted, and restricted means that row has prior authorization, step therapy, or a quantity limit.

A plan with no row for the drug counts as not listing it. That can be a product the file codes another way, so read a low count as a lookup result, not a coverage decision. A state counts every plan the CMS landscape file offers there. Parent organizations are named as CMS names them. The drug list is the top 200 by total Part D spending.

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page

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