FDA label
What is aprepitant used for?
The FDA-approved uses of aprepitant, quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label for aprepitant lists 2 uses: Prevention of Chemotherapy Induced Nausea and Vomiting (CINV); Prevention of Postoperative Nausea and Vomiting (PONV).
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Aprepitant, capsule
Indications and Usage, quoted from the label by Torrent Pharmaceuticals Limited (ANDA211835). Cross-references to other label sections are left out.
Prevention of Chemotherapy Induced Nausea and Vomiting (CINV)
Aprepitant capsules, in combination with other antiemetic agents, is indicated in patients 12 years of age and older for the prevention of:
- acute and delayed nausea and vomiting associted with initial and repeat courses of highly emetogenic cancer chemotherapy (HEC) including high-dose cisplatin.
- nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy (MEC).
Prevention of Postoperative Nausea and Vomiting (PONV)
Aprepitant capsules are indicated in adults for the prevention of postoperative nausea and vomiting.
Limitations of Use
- Aprepitant has not been studied for the treatment of established nausea and vomiting.
- Chronic continuous administration of Aprepitant is not recommended because it has not been studied, and because the drug interaction profile may change during chronic continuous use.
Source: DailyMed label, set id af9b6086-4bf2-472c-8740-4134eaaebace, version 9, effective June 11, 2026. NDC 13668-591, one of 15 listings for this product.
Questions
What is aprepitant used for?
The FDA label for aprepitant lists 2 uses: Prevention of Chemotherapy Induced Nausea and Vomiting (CINV); Prevention of Postoperative Nausea and Vomiting (PONV).
What drug class is aprepitant?
FDA lists aprepitant in the Substance P/Neurokinin-1 Receptor Antagonist established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.
More on Aprepitant
- Is Aprepitant a controlled substance?Federal schedule
- Generic for EmendFDA Orange Book
- Generic for AponvieFDA Orange Book
- Generic for CinvantiFDA Orange Book
- Substance P/Neurokinin-1 Receptor Antagonists listFDA drug class
- NDC 0006-0461Aprepitant NDC record
- NDC 0006-0462Aprepitant NDC record
- NDC 0006-0464Aprepitant NDC record