What is hydroxychloroquine used for?

Indications and Usage, quoted from the label by Dr. Reddy's Laboratories Inc. (ANDA210441). Cross-references to other label sections are left out.

Malaria

Hydroxychloroquine sulfate tablets are indicated in adult and pediatric patients for the:

• Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium vivax, and Plasmodium ovale.
• Prophylaxis of malaria in geographic areas where chloroquine resistance is not reported.

Limitations of Use:

Hydroxychloroquine sulfate tablets are not recommended for:

• Treatment of complicated malaria.
• Treatment of malaria by chloroquine or hydroxychloroquine-resistant strains of Plasmodium species.
• Treatment of malaria acquired in geographic areas where chloroquine resistance occurs or when the Plasmodium species has not been identified.
• Prophylaxis of malaria in geographic areas where chloroquine resistance occurs.
• Prevention of relapses of P. vivax or P. ovale because it is not active against the hypnozoite liver stage forms of these parasites. For radical cure of P. vivax and P. ovale infections, concomitant therapy with an 8-aminoquinoline drug is necessary.

For the most current information about drug resistance, refer to the latest recommendations from the Center for Disease Control and Prevention1.

Rheumatoid Arthritis

Hydroxychloroquine sulfate tablets are indicated for the treatment of acute and chronic rheumatoid arthritis in adults.

Systemic Lupus Erythematosus

Hydroxychloroquine sulfate tablets are indicated for the treatment of systemic lupus erythematosus in adults.

Chronic Discoid Lupus Erythematosus

Hydroxychloroquine sulfate tablets are indicated for the treatment of chronic discoid lupus erythematosus in adults.

Source: DailyMed label, set id 452092b4-7a8f-4d19-8113-f1c2a948d3d8, version 17, effective December 5, 2025. NDC 43598-131, one of 37 listings for this product.

Indications and Usage, quoted from the label by Accord Healthcare, Inc., (ANDA213342). Cross-references to other label sections are left out.

Malaria

Hydroxychloroquine sulfate is indicated in adult and pediatric patients for the:

• Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium vivax,and Plasmodium ovale.
• Prophylaxis of malaria in geographic areas where chloroquine resistance is not reported.

Limitations of Use:

Hydroxychloroquine sulfate is notrecommended for:

• Treatment of complicated malaria.
• Treatment of malaria by chloroquine or hydroxychloroquine-resistant strains of Plasmodiumspecies [see Microbiology].
• Treatment of malaria acquired in geographic areas where chloroquine resistance occurs or when the Plasmodiumspecies has not been identified.
• Prophylaxis of malaria in geographic areas where chloroquine resistance occurs.
• Prevention of relapses of P. vivaxor P. ovalebecause it is not active against the hypnozoite liver stage forms of these parasites. For radical cure of P. vivaxand P. ovaleinfections, concomitant therapy with an 8-aminoquinoline drug is necessary [see Microbiology].

For the most current information about drug resistance, refer to the latest recommendations from the Center for Disease Control and Prevention 1.

Rheumatoid Arthritis

Hydroxychloroquine sulfate is indicated for the treatment of acute and chronic rheumatoid arthritis in adults.

Systemic Lupus Erythematosus

Hydroxychloroquine sulfate is indicated for the treatment of systemic lupus erythematosus in adults.

Chronic Discoid Lupus Erythematosus

Hydroxychloroquine sulfate is indicated for the treatment of chronic discoid lupus erythematosus in adults.

Source: DailyMed label, set id 84b00366-96ef-41e1-bac6-5d24acdb9e1d, version 10, effective April 1, 2026. NDC 16729-485, one of 16 listings for this product.