What Is Lamivudine Used For? FDA-Approved Uses

The FDA label says: “Lamivudine tablets (HBV) are indicated for the treatment of chronic hepatitis B virus (HBV) infection associated with evidence of hepatitis B viral replication and active liver inflammation.”

Run it in Rivvi

Which 2027 plans near you dropped or restricted lamivudine?

Tier changes and new prior auth, step therapy or quantity limits, plan by plan.

Free to start. Opens Rivvi, the AI workspace for healthcare teams.

Lamivudine, tablet, film coated

Indications and Usage, quoted from the label by Apotex Corp. (ANDA202941). Cross-references to other label sections are left out.

Lamivudine tablets (HBV) are indicated for the treatment of chronic hepatitis B virus (HBV) infection associated with evidence of hepatitis B viral replication and active liver inflammation.
The following points should be considered when initiating therapy with lamivudine tablets (HBV):
Due to high rates of resistance development in treated patients, initiation of treatment with lamivudine tablets (HBV) should only be considered when the use of an alternative antiviral agent with a higher genetic barrier to resistance is not available or appropriate.
Lamivudine tablets (HBV) have not been evaluated in patients co-infected with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis delta virus.
Lamivudine tablets (HBV) have not been evaluated in liver transplant recipients or in patients with chronic hepatitis B virus infection with decompensated liver disease.

Source: DailyMed label, set id 87095352-c088-74b1-7be0-d3e293a90611, version 12, effective September 14, 2026. NDC 60505-3250, one of 20 listings for this product.

Lamivudine Oral, solution

Indications and Usage, quoted from the label by Chartwell Govermental & Specialty RX, LLC. (ANDA203564). Cross-references to other label sections are left out.

Lamivudine oral solution, USP is a nucleoside analogue indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection.
Limitations of Use:
The dosage of this product is for HIV-1 and not for HBV.

Source: DailyMed label, set id b23aea53-324b-4ff2-8736-639e4045e388, version 2, effective January 2, 2026. NDC 68999-706, one of 4 listings for this product.

Questions

What is lamivudine used for?

The FDA label says: “Lamivudine tablets (HBV) are indicated for the treatment of chronic hepatitis B virus (HBV) infection associated with evidence of hepatitis B viral replication and active liver inflammation.”

What drug class is lamivudine?

FDA lists lamivudine in the Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor and Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor established pharmacologic class.

Does this page cover off-label uses or dosing?

No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.