FDA label
What is liothyronine used for?
The FDA-approved uses of liothyronine, quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label for liothyronine sodium (tablet) lists 3 uses: Hypothyroidism; Pituitary Thyrotropin (Thyroid-Stimulating Hormone, TSH) Suppression; Thyroid Suppression Test.
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Liothyronine Sodium, tablet
Indications and Usage, quoted from the label by Sun Pharmaceutical Industries, Inc. (ANDA091382). Cross-references to other label sections are left out.
Hypothyroidism
Liothyronine sodium tablets are indicated as a replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism.
Pituitary Thyrotropin (Thyroid-Stimulating Hormone, TSH) Suppression
Liothyronine sodium tablets are indicated as an adjunct to surgery and radioiodine therapy in the management of well-differentiated thyroid cancer.
Thyroid Suppression Test
Liothyronine sodium tablets are indicated as a diagnostic agent in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland autonomy. Limitations of Use
- Liothyronine sodium tablets are not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients as there are no clinical benefits and overtreatment with liothyronine sodium tablets may induce hyperthyroidism.
- Liothyronine sodium tablets are not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis.
Source: DailyMed label, set id 892e63ef-3a60-45fa-b12b-d6795acc0956, version 5, effective October 3, 2023. NDC 62756-589, one of 44 listings for this product.
Liothyronine Sodium, injection, solution
Indications and Usage, quoted from the label by XGen Pharmaceuticals DJB, Inc. (ANDA076923). Cross-references to other label sections are left out.
Liothyronine sodium injection (T 3) is indicated in the treatment of myxedema coma/precoma.
Liothyronine sodium injection (T 3) can be used in patients allergic to desiccated thyroid or thyroid extract derived from pork or beef.
Source: DailyMed label, set id a8b39730-de19-497d-bde8-6594aa528403, version 17, effective December 1, 2023. NDC 39822-0151, one of 1 listing for this product.
Questions
What is liothyronine used for?
The FDA label for liothyronine sodium (tablet) lists 3 uses: Hypothyroidism; Pituitary Thyrotropin (Thyroid-Stimulating Hormone, TSH) Suppression; Thyroid Suppression Test.
What drug class is liothyronine?
FDA lists liothyronine in the l-Triiodothyronine established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.