FDA label

What is methohexital used for?

The FDA-approved uses of methohexital, quoted from the Indications and Usage section of its DailyMed label.

Source: DailyMed SPL label file dated 2026-10-23. Publisher page

The FDA label says: “Methohexital Sodium for Injection can be used in adults as follows: For intravenous induction of anesthesia prior to the use of other general anesthetic agents; For intravenous induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for short surgical procedures; Methohexital Sodium for Injection may be given by infusion or intermi...”

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Methohexital Sodium, injection

Indications and Usage, quoted from the label by Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. (ANDA215488). Cross-references to other label sections are left out.

Methohexital Sodium for Injection can be used in adults as follows:

  • For intravenous induction of anesthesia prior to the use of other general anesthetic agents.
  • For intravenous induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for short surgical procedures; Methohexital Sodium for Injection may be given by infusion or intermittent injection.
  • For use along with other parenteral agents, usually narcotic analgesics, to supplement subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for longer surgical procedures.
  • As intravenous anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli (See WARNINGS ).
  • As an agent for inducing a hypnotic state.

Methohexital Sodium for Injection can be used in pediatric patients older than 1 month as follows:

  • For rectal or intramuscular induction of anesthesia prior to the use of other general anesthetic agents.
  • For rectal or intramuscular induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents for short surgical procedures.
  • As rectal or intramuscular anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli.

Source: DailyMed label, set id f76d4ab9-2f6c-420b-afec-b9cdfdc083ce, version 3, effective July 27, 2026. NDC 23155-893, one of 2 listings for this product.

Questions

What is methohexital used for?

The FDA label says: “Methohexital Sodium for Injection can be used in adults as follows: For intravenous induction of anesthesia prior to the use of other general anesthetic agents; For intravenous induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for short surgical procedures; Methohexital Sodium for Injection may be given by infusion or intermi...”

What drug class is methohexital?

FDA lists methohexital in the Barbiturate established pharmacologic class.

Does this page cover off-label uses or dosing?

No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.

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