FDA label
What is Numbrino used for?
Numbrino contains cocaine. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “NUMBRINO (cocaine hydrochloride) nasal solution is indicated for the induction of local anesthesia of the mucous membranes when performing diagnostic procedures and surgeries on or through the nasal cavities in adults.”
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Numbrino, solution
Indications and Usage, quoted from the label by OMNIVIUM PHARMACEUTICALS LLC. (NDA209575). Cross-references to other label sections are left out.
NUMBRINO (cocaine hydrochloride) nasal solution is indicated for the induction of local anesthesia of the mucous membranes when performing diagnostic procedures and surgeries on or through the nasal cavities in adults.
Source: DailyMed label, set id d724b5b4-6654-4bf5-9eed-e2c7943084ed, version 3, effective January 12, 2026. NDC 81665-300, one of 1 listing for this product.
Questions
What is Numbrino used for?
The FDA label says: “NUMBRINO (cocaine hydrochloride) nasal solution is indicated for the induction of local anesthesia of the mucous membranes when performing diagnostic procedures and surgeries on or through the nasal cavities in adults.”
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.