FDA label
What is Nuzyra used for?
Nuzyra contains omadacycline. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label for Nuzyra lists 3 uses: Community-Acquired Bacterial Pneumonia; Acute Bacterial Skin and Skin Structure Infections; Usage.
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Indications and Usage, quoted from the label by Paratek Pharmaceuticals, Inc. (NDA209817). Cross-references to other label sections are left out.
Community-Acquired Bacterial Pneumonia
NUZYRA is indicated for the treatment of adult patients with community-acquired bacterial pneumonia (CABP) caused by the following susceptible microorganisms: Streptococcus pneumoniae, Staphylococcus aureus(methicillin-susceptible isolates), Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae,and Chlamydophila pneumoniae.
Acute Bacterial Skin and Skin Structure Infections
NUZYRA is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused by the following susceptible microorganisms: Staphylococcus aureus(methicillin-susceptible and -resistant isolates), Staphylococcus lugdunensis, Streptococcus pyogenes, Streptococcus anginosusgrp. (includes S. anginosus, S. intermedius, and S. constellatus), Enterococcus faecalis, Enterobacter cloacae,and Klebsiella pneumoniae.
Usage
To reduce the development of drug-resistant bacteria and maintain the effectiveness of NUZYRA and other antibacterial drugs, NUZYRA should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Source: DailyMed label, set id 51591524-4703-44c6-8bde-dce3e6a463d1, version 12, effective May 27, 2026. NDC 71715-001, one of 1 listing for this product.
Questions
What is Nuzyra used for?
The FDA label for Nuzyra lists 3 uses: Community-Acquired Bacterial Pneumonia; Acute Bacterial Skin and Skin Structure Infections; Usage.
What drug class is Nuzyra?
FDA lists omadacycline in the Tetracycline-class Antibacterial established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.