FDA label
What is Zoloft used for?
Zoloft contains sertraline. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “ZOLOFT is indicated for the treatment of the following: Major depressive disorder (MDD); Obsessive-compulsive disorder (OCD); Panic disorder (PD); Posttraumatic stress disorder (PTSD); Social anxiety disorder (SAD); Premenstrual dysphoric disorder (PMDD).”
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Zoloft, tablet, film coated
Indications and Usage, quoted from the label by Viatris Specialty LLC (NDA019839). Cross-references to other label sections are left out.
ZOLOFT is indicated for the treatment of the following:
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Posttraumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
Source: DailyMed label, set id fda754f6-d0f3-4dce-a17a-927d64f912f7, version 7, effective August 8, 2023. NDC 58151-574, one of 3 listings for this product.
Questions
What is Zoloft used for?
The FDA label says: “ZOLOFT is indicated for the treatment of the following: Major depressive disorder (MDD); Obsessive-compulsive disorder (OCD); Panic disorder (PD); Posttraumatic stress disorder (PTSD); Social anxiety disorder (SAD); Premenstrual dysphoric disorder (PMDD).”
What drug class is Zoloft?
FDA lists sertraline in the Serotonin Reuptake Inhibitor established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.
More on Zoloft
- Is Zoloft a controlled substance?Federal schedule
- Generic for ZoloftFDA Orange Book
- What is Sertraline used for?FDA label uses
- Is Sertraline a controlled substance?Federal schedule
- Serotonin Reuptake Inhibitors listFDA drug class
- NDC 58151-574Zoloft NDC record
- NDC 58151-575Zoloft NDC record
- NDC 58151-576Zoloft NDC record