ICD-10-CM
ICD-10 code for Reaction toxic, to local anesthesia: T88.59
The ICD-10-CM index points "Reaction toxic, to local anesthesia" to T88.59, Other complications of anesthesia. T88.59 is not billable on its own. Add the 7th character for the encounter, for example T88.59XA, Other complications of anesthesia, initial encounter.
Source: CDC ICD-10-CM FY2027 Alphabetic Index file dated June 16, 2026. Publisher page
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Index subterms
A header groups codes and is not billed. A billable code is one you can report.
More specific codes in T88
A header groups codes and is not billed. A billable code is one you can report.
- T88Other complications of surgical and medical care, not elsewhere classifiedHeader
- T88.0Infection following immunizationHeader
- T88.0XXAInfection following immunization, initial encounterBillable
- T88.0XXDInfection following immunization, subsequent encounterBillable
- T88.0XXSInfection following immunization, sequelaBillable
- T88.1Other complications following immunization, not elsewhere classifiedHeader
- T88.1XXAOther complications following immunization, not elsewhere classified, initial encounterBillable
- T88.1XXDOther complications following immunization, not elsewhere classified, subsequent encounterBillable
- T88.1XXSOther complications following immunization, not elsewhere classified, sequelaBillable
- T88.2Shock due to anesthesiaHeader
- T88.2XXAShock due to anesthesia, initial encounterBillable
- T88.2XXDShock due to anesthesia, subsequent encounterBillable
- T88.2XXSShock due to anesthesia, sequelaBillable
- T88.3Malignant hyperthermia due to anesthesiaHeader
- T88.3XXAMalignant hyperthermia due to anesthesia, initial encounterBillable
- T88.3XXDMalignant hyperthermia due to anesthesia, subsequent encounterBillable
- T88.3XXSMalignant hyperthermia due to anesthesia, sequelaBillable
- T88.4Failed or difficult intubationHeader
- T88.4XXAFailed or difficult intubation, initial encounterBillable
- T88.4XXDFailed or difficult intubation, subsequent encounterBillable
- T88.4XXSFailed or difficult intubation, sequelaBillable
- T88.5Other complications of anesthesiaHeader
- T88.51Hypothermia following anesthesiaHeader
- T88.51XAHypothermia following anesthesia, initial encounterBillable
- T88.51XDHypothermia following anesthesia, subsequent encounterBillable
- T88.51XSHypothermia following anesthesia, sequelaBillable
- T88.52Failed moderate sedation during procedureHeader
- T88.52XAFailed moderate sedation during procedure, initial encounterBillable
- T88.52XDFailed moderate sedation during procedure, subsequent encounterBillable
- T88.52XSFailed moderate sedation during procedure, sequelaBillable
- T88.53Unintended awareness under general anesthesia during procedureHeader
- T88.53XAUnintended awareness under general anesthesia during procedure, initial encounterBillable
- T88.53XDUnintended awareness under general anesthesia during procedure, subsequent encounterBillable
- T88.53XSUnintended awareness under general anesthesia during procedure, sequelaBillable
- T88.59Other complications of anesthesiaHeader
- T88.59XAOther complications of anesthesia, initial encounterBillable
- T88.59XDOther complications of anesthesia, subsequent encounterBillable
- T88.59XSOther complications of anesthesia, sequelaBillable
- T88.6Anaphylactic reaction due to adverse effect of correct drug or medicament properly administeredHeader
- T88.6XXAAnaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounterBillable
- T88.6XXDAnaphylactic reaction due to adverse effect of correct drug or medicament properly administered, subsequent encounterBillable
- T88.6XXSAnaphylactic reaction due to adverse effect of correct drug or medicament properly administered, sequelaBillable
- T88.7Unspecified adverse effect of drug or medicamentHeader
- T88.7XXAUnspecified adverse effect of drug or medicament, initial encounterBillable
- T88.7XXDUnspecified adverse effect of drug or medicament, subsequent encounterBillable
- T88.7XXSUnspecified adverse effect of drug or medicament, sequelaBillable
- T88.8Other specified complications of surgical and medical care, not elsewhere classifiedHeader
- T88.8XXAOther specified complications of surgical and medical care, not elsewhere classified, initial encounterBillable
- T88.8XXDOther specified complications of surgical and medical care, not elsewhere classified, subsequent encounterBillable
- T88.8XXSOther specified complications of surgical and medical care, not elsewhere classified, sequelaBillable
- T88.9Complication of surgical and medical care, unspecifiedHeader
- T88.9XXAComplication of surgical and medical care, unspecified, initial encounterBillable
- T88.9XXDComplication of surgical and medical care, unspecified, subsequent encounterBillable
- T88.9XXSComplication of surgical and medical care, unspecified, sequelaBillable
Use additional code
The CDC tabular list says to add the code named here after this one when it applies.
From T88.5. A note on a category applies to every code under it.
Use additional code for adverse effect, if applicable, to identify drug (T41.- with fifth or sixth character 5)
Excludes2
Excludes2 means the other condition can be reported with this one when both are documented.
From T88. A note on a category applies to every code under it.
- T80.-Complication following infusion, transfusion and therapeutic injection
- T81.-Complication following procedure NEC
- O74.-Complications of anesthesia in labor and delivery
- O29.-Complications of anesthesia in pregnancy
- O89.-Complications of anesthesia in puerperium
- T82-T85Complications of devices, implants and grafts
- O75.4Complications of obstetric surgery and procedure
- L23.3, L24.4, L25.1, L27.0-L27.1Dermatitis due to drugs and medicaments
- T36-T65 with fifth or sixth character 1-4Poisoning and toxic effects of drugs and chemicals
- specified complications classified elsewhere
Related pages
- T88.59 code detailsNotes, nearby codes, CMS-HCC group
- Category T88Every code under it
- Chapter 19Injury, poisoning and certain other consequences
- ICD-10 codes by conditionA to Z
- Check a list of ICD-10 codes
- Denial code CO-11Diagnosis does not support the procedure
- Denial code CO-146Diagnosis invalid for the date of service
- HCPCS Level II code lookup
Questions
What is the ICD-10 code for Reaction toxic, to local anesthesia?
The ICD-10-CM index points "Reaction toxic, to local anesthesia" to T88.59, Other complications of anesthesia. T88.59 is not billable on its own. Add the 7th character for the encounter, for example T88.59XA, Other complications of anesthesia, initial encounter.
Is T88.59 billable?
No. T88.59 is a header in the FY2027 CDC file. Report a more specific code under it.
What documentation notes apply to T88.59?
The CDC tabular list gives 10 Excludes2 notes (may be coded together when both are documented), 1 "use additional code" note for T88.59 and the categories above it. They are listed on this page.
What chapter is T88.59 in?
Chapter 19. Injury, poisoning and certain other consequences.
When do ICD-10-CM codes change?
Every October 1, with the new fiscal year file. Some years add April 1 updates. This page uses the FY2027 file, effective October 1, 2026.