ICD-10-CM
ICD-10 code for Tumor lysis syndrome: E88.3
The closest CDC title for "Tumor lysis syndrome" is E88.3, Tumor lysis syndrome. E88.3 is a billable code.
Source: CDC ICD-10-CM FY2027 order file dated June 16, 2026. Publisher page
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Codes under E88, then other CDC titles that name tumor lysis syndrome
A header groups codes and is not billed. A billable code is one you can report.
- E88Other and unspecified metabolic disordersHeader
- E88.0Disorders of plasma-protein metabolism, not elsewhere classifiedHeader
- E88.01Alpha-1-antitrypsin deficiencyBillable
- E88.02Plasminogen deficiencyBillable
- E88.09Other disorders of plasma-protein metabolism, not elsewhere classifiedBillable
- E88.1Lipodystrophy, not elsewhere classifiedHeader
- E88.10Lipodystrophy, unspecifiedBillable
- E88.11Partial lipodystrophyBillable
- E88.12Generalized lipodystrophyBillable
- E88.13Localized lipodystrophyBillable
- E88.14HIV-associated lipodystrophyBillable
- E88.19Other lipodystrophy, not elsewhere classifiedBillable
- E88.2Lipomatosis, not elsewhere classifiedBillable
- E88.3Tumor lysis syndromeBillable
- E88.4Mitochondrial metabolism disordersHeader
- E88.40Mitochondrial metabolism disorder, unspecifiedBillable
- E88.41MELAS syndromeBillable
- E88.42MERRF syndromeBillable
- E88.43Disorders of mitochondrial tRNA synthetasesBillable
- E88.49Other mitochondrial metabolism disordersBillable
- E88.8Other specified metabolic disordersHeader
- E88.81Metabolic syndrome and other insulin resistanceHeader
- E88.810Metabolic syndromeBillable
- E88.811Insulin resistance syndrome, Type ABillable
- E88.818Other insulin resistanceBillable
- E88.819Insulin resistance, unspecifiedBillable
- E88.82Obesity due to disruption of MC4R pathwayBillable
- E88.89Other specified metabolic disordersBillable
- E88.9Metabolic disorder, unspecifiedBillable
- E88.AWasting disease (syndrome) due to underlying conditionBillable
Use additional code
The CDC tabular list says to add the code named here after this one when it applies.
Use additional code for adverse effect, if applicable, to identify drug (T45.1X5)
From E88. A note on a category applies to every code under it.
Use additional codes for associated conditions
Excludes1
Excludes1 means these codes are not reported together.
From E88. A note on a category applies to every code under it.
Related conditions
Related pages
- E88.3 code detailsNotes, nearby codes, CMS-HCC group
- Category E88Every code under it
- Chapter 4Endocrine, nutritional and metabolic diseases
- ICD-10 codes by conditionA to Z
- Check a list of ICD-10 codes
- Denial code CO-11Diagnosis does not support the procedure
- Denial code CO-146Diagnosis invalid for the date of service
- HCPCS Level II code lookup
Questions
What is the ICD-10 code for Tumor lysis syndrome?
The closest CDC title for "Tumor lysis syndrome" is E88.3, Tumor lysis syndrome. E88.3 is a billable code.
Is E88.3 billable?
Yes. E88.3 is a billable code in the FY2027 ICD-10-CM file. Use a more specific code when the record documents one.
What documentation notes apply to E88.3?
The CDC tabular list gives 1 Excludes1 note (not coded together), 2 "use additional code" notes for E88.3 and the categories above it. They are listed on this page.
What chapter is E88.3 in?
Chapter 4. Endocrine, nutritional and metabolic diseases.
When do ICD-10-CM codes change?
Every October 1, with the new fiscal year file. Some years add April 1 updates. This page uses the FY2027 file, effective October 1, 2026.