HCPCS Level II modifier
Modifier EA
Modifier EA is a HCPCS Level II modifier. CMS describes it as: Erythropoietic stimulating agent (ESA) administered to treat anemia due to anti-cancer chemotherapy.
Source: CMS HCPCS Level II, October 2026 file dated September 23, 2026. Publisher page
Run it in Rivvi
Check the codes on your claims export
Upload a claims export. Rivvi flags ICD-10 and HCPCS codes that are not billable or are replaced. It does not check modifiers.
Check my exportFree to start. Opens Rivvi, the AI workspace for healthcare teams.
- Modifier
- EA
- Type
- HCPCS Level II modifier, maintained by CMS
- CMS description
- Erythropoietic stimulating agent (ESA) administered to treat anemia due to anti-cancer chemotherapy
- Claim form
- CMS-1500 item 24D, up to four modifiers per line. 837P SV101-3 to SV101-6.
- Guidance
- CMS HCPCS quarterly update
Related modifiers
- EBErythropoietic stimulating agent (ESA) administered to treat anemia due to anti-cancer radiotherapy
- E4Lower right, eyelid
- ECErythropoietic stimulating agent (ESA) administered to treat anemia not due to anti-cancer radiotherapy or anti-cancer chemotherapy
- E3Upper right, eyelid
- EDHematocrit level has exceeded 39% (or hemoglobin level has exceeded 13.0 g/dl) for 3 or more consecutive billing cycles immediately prior to and including the current cycle
- E2Lower left, eyelid
- EEHematocrit level has not exceeded 39% (or hemoglobin level has not exceeded 13.0 g/dl) for 3 or more consecutive billing cycles immediately prior to and including the current cycle
- E1Upper left, eyelid
Related pages
Questions
What does modifier EA mean?
Modifier EA is a HCPCS Level II modifier. CMS describes it as: Erythropoietic stimulating agent (ESA) administered to treat anemia due to anti-cancer chemotherapy.
Is modifier EA a CPT or a HCPCS modifier?
EA is a HCPCS Level II modifier from the CMS quarterly HCPCS file. Two-digit numeric modifiers, such as 25 or 59, are CPT modifiers.
Where does modifier EA go on a claim?
On the CMS-1500 it goes in item 24D next to the procedure code. Each line holds up to four modifiers. On an 837P it goes in SV101-3 to SV101-6.
What denial comes back when a modifier is wrong?
A missing or mismatched modifier often comes back as CARC 4. A modifier that was not valid on the date of service comes back as CARC 182. A bundling edit the modifier should have bypassed comes back as CARC 97 or 236.