DEA schedule
Is difenoxin and atropine a controlled substance?
Federal schedule for difenoxin and atropine from the FDA NDC directory, checked against the DEA controlled substances list.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
Yes. Difenoxin and atropine is a Schedule IV controlled substance under the federal Controlled Substances Act. Matching DEA list entry: Difenoxin 1 mg/25 ug AtSO4/du (Schedule IV).
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Schedule check
| Source | What it lists |
|---|---|
| FDA NDC directory | 2 prescription listings from 2 labelers, all Schedule IV |
| DEA controlled substances list | Difenoxin: Schedule I; Difenoxin 1 mg/25 ug AtSO4/du: Schedule IV; Difenoxin preparations - 0.5 mg/25 ug AtSO4/du: Schedule V |
DEA list entry
| Substance | DEA code | Schedule | Narcotic | Other names | Match |
|---|---|---|---|---|---|
| Difenoxin | 9168 | I | Yes | Lyspafen | Listed by name |
| Difenoxin 1 mg/25 ug AtSO4/du | 9167 | IV | Yes | Motofen | Listed combination or preparation |
| Difenoxin preparations - 0.5 mg/25 ug AtSO4/du | None | V | Yes | Motofen | Listed combination or preparation |
Difenoxin and Atropine NDC listings
Questions
Is difenoxin and atropine a controlled substance?
Yes. Difenoxin and atropine is a Schedule IV controlled substance under the federal Controlled Substances Act. Matching DEA list entry: Difenoxin 1 mg/25 ug AtSO4/du (Schedule IV).
Is difenoxin and atropine a narcotic?
Yes. The DEA list marks difenoxin and atropine as a narcotic (NARC = Y) and places it in Schedule IV. Its FDA established pharmacologic class is Anticholinergic and Antidiarrheal and Cholinergic Muscarinic Antagonist.
What schedule is difenoxin and atropine?
Difenoxin and atropine is Schedule IV in the FDA NDC directory, which matches the DEA controlled substances list.
Does this page cover state schedules?
No. This page reports the federal schedule only. Some states schedule drugs on their own; check your state board of pharmacy.
More on Difenoxin and Atropine
- What is Difenoxin and Atropine used for?FDA label uses
- Generic for MotofenFDA Orange Book
- Is Motofen a controlled substance?Schedule IV
- Anticholinergics listFDA drug class
- Antidiarrheals listFDA drug class
- Cholinergic Muscarinic Antagonists listFDA drug class
- NDC 54766-200Difenoxin and Atropine NDC record
- NDC 83107-011Difenoxin and Atropine NDC record
- Schedule IV drugs listDEA schedule