DEA schedule
Is Entresto a controlled substance?
Entresto contains sacubitril and valsartan. Federal schedule from the FDA NDC directory, checked against the DEA controlled substances list.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
No. Entresto (sacubitril and valsartan) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and sacubitril and valsartan is not on the DEA controlled substances list.
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Schedule check
| Source | What it lists |
|---|---|
| FDA NDC directory | 10 prescription listings from 2 labelers, none with a DEA schedule |
| DEA controlled substances list | sacubitril and valsartan is not on the list |
Entresto NDC listings
| NDC | Product | Form | Strength | Labeler | DEA schedule |
|---|---|---|---|---|---|
| 0078-1238 | ENTRESTO | pellet | 15 mg/1; 16 mg/1 | Novartis Pharmaceuticals Corporation | None |
| 0078-1231 | ENTRESTO | pellet | 6 mg/1; 6 mg/1 | Novartis Pharmaceuticals Corporation | None |
| 0078-0659 | ENTRESTO | tablet, film coated | 24 mg/1; 26 mg/1 | Novartis Pharmaceuticals Corporation | None |
| 0078-9659 | ENTRESTO | tablet, film coated | 24 mg/1; 26 mg/1 | Novartis Pharmaceuticals Corporation | None |
| 71610-810 | ENTRESTO | tablet, film coated | 24 mg/1; 26 mg/1 | Aphena Pharma Solutions - Tennessee, LLC | None |
| 0078-0777 | ENTRESTO | tablet, film coated | 49 mg/1; 51 mg/1 | Novartis Pharmaceuticals Corporation | None |
| 0078-9777 | ENTRESTO | tablet, film coated | 49 mg/1; 51 mg/1 | Novartis Pharmaceuticals Corporation | None |
| 71610-806 | ENTRESTO | tablet, film coated | 49 mg/1; 51 mg/1 | Aphena Pharma Solutions - Tennessee, LLC | None |
| 0078-0696 | ENTRESTO | tablet, film coated | 97 mg/1; 103 mg/1 | Novartis Pharmaceuticals Corporation | None |
| 71610-807 | ENTRESTO | tablet, film coated | 97 mg/1; 103 mg/1 | Aphena Pharma Solutions - Tennessee, LLC | None |
Questions
Is Entresto a controlled substance?
No. Entresto (sacubitril and valsartan) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and sacubitril and valsartan is not on the DEA controlled substances list.
Is Entresto a narcotic?
No. Entresto (sacubitril and valsartan) is not on the DEA controlled substances list, so the DEA does not classify it as a narcotic. Its FDA established pharmacologic class is Angiotensin 2 Receptor Blocker and Neprilysin Inhibitor.
Does this page cover state schedules?
No. This page reports the federal schedule only. Some states schedule drugs on their own; check your state board of pharmacy.
More on Entresto
- What is Entresto used for?FDA label uses
- Generic for EntrestoFDA Orange Book
- Generic for Entresto SprinkleFDA Orange Book
- Angiotensin 2 Receptor Blockers listFDA drug class
- Neprilysin Inhibitors listFDA drug class
- Entresto Medicare Part D coverageBy plan and state
- NDC 0078-0659Entresto NDC record
- NDC 0078-0696Entresto NDC record
- NDC 0078-0777Entresto NDC record