DEA schedule
Is Linzess a controlled substance?
Linzess contains linaclotide. Federal schedule from the FDA NDC directory, checked against the DEA controlled substances list.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
No. Linzess (linaclotide) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and linaclotide is not on the DEA controlled substances list.
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Schedule check
| Source | What it lists |
|---|---|
| FDA NDC directory | 4 prescription listings from 2 labelers, none with a DEA schedule |
| DEA controlled substances list | linaclotide is not on the list |
Linzess NDC listings
| NDC | Product | Form | Strength | Labeler | DEA schedule |
|---|---|---|---|---|---|
| 0456-1201 | Linzess | capsule, gelatin coated | 145 ug/1 | Allergan, Inc. | None |
| 50090-8108 | LINZESS | capsule, gelatin coated | 145 ug/1 | A-S Medication Solutions | None |
| 0456-1202 | Linzess | capsule, gelatin coated | 290 ug/1 | Allergan, Inc. | None |
| 0456-1203 | Linzess | capsule, gelatin coated | 72 ug/1 | Allergan, Inc. | None |
Questions
Is Linzess a controlled substance?
No. Linzess (linaclotide) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and linaclotide is not on the DEA controlled substances list.
Is Linzess a narcotic?
No. Linzess (linaclotide) is not on the DEA controlled substances list, so the DEA does not classify it as a narcotic. Its FDA established pharmacologic class is Guanylate Cyclase-C Agonist.
Does this page cover state schedules?
No. This page reports the federal schedule only. Some states schedule drugs on their own; check your state board of pharmacy.