DEA schedule
Is Prolia a controlled substance?
Prolia contains denosumab. Federal schedule from the FDA NDC directory, checked against the DEA controlled substances list.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
No. Prolia (denosumab) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and denosumab is not on the DEA controlled substances list.
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Schedule check
| Source | What it lists |
|---|---|
| FDA NDC directory | 1 prescription listings from 1 labelers, none with a DEA schedule |
| DEA controlled substances list | denosumab is not on the list |
Prolia NDC listings
| NDC | Product | Form | Strength | Labeler | DEA schedule |
|---|---|---|---|---|---|
| 55513-710 | Prolia | injection | 60 mg/mL | Amgen, Inc | None |
Questions
Is Prolia a controlled substance?
No. Prolia (denosumab) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and denosumab is not on the DEA controlled substances list.
Is Prolia a narcotic?
No. Prolia (denosumab) is not on the DEA controlled substances list, so the DEA does not classify it as a narcotic. Its FDA established pharmacologic class is RANK Ligand Inhibitor.
Does this page cover state schedules?
No. This page reports the federal schedule only. Some states schedule drugs on their own; check your state board of pharmacy.