DEA schedule
Is Spravato a controlled substance?
Spravato contains esketamine. Federal schedule from the FDA NDC directory, checked against the DEA controlled substances list.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
Yes. Spravato (esketamine) is a Schedule III controlled substance under the federal Controlled Substances Act. Matching DEA list entry: Ketamine (Schedule III).
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Schedule check
| Source | What it lists |
|---|---|
| FDA NDC directory | 1 prescription listings from 1 labelers, all Schedule III |
| DEA controlled substances list | Ketamine: Schedule III |
DEA list entry
| Substance | DEA code | Schedule | Narcotic | Other names | Match |
|---|---|---|---|---|---|
| Ketamine | 7285 | III | No | Ketaset; Ketalar; Special K; K | Isomer or salt of the listed substance (21 CFR 1308) |
Spravato NDC listings
| NDC | Product | Form | Strength | Labeler | DEA schedule |
|---|---|---|---|---|---|
| 50458-028 | Spravato | solution | 28 mg/.2mL | Janssen Pharmaceuticals, Inc. | CIII |
Questions
Is Spravato a controlled substance?
Yes. Spravato (esketamine) is a Schedule III controlled substance under the federal Controlled Substances Act. Matching DEA list entry: Ketamine (Schedule III).
Is Spravato a narcotic?
No. The DEA list does not mark esketamine as a narcotic (NARC = N) and places it in Schedule III.
What schedule is Spravato?
Spravato is Schedule III in the FDA NDC directory, which matches the DEA controlled substances list.
Does this page cover state schedules?
No. This page reports the federal schedule only. Some states schedule drugs on their own; check your state board of pharmacy.