DEA schedule

Is Zoryve a controlled substance?

Zoryve contains roflumilast. Federal schedule from the FDA NDC directory, checked against the DEA controlled substances list.

Source: FDA NDC Directory file dated 2026-10-22. Publisher page

No. Zoryve (roflumilast) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and roflumilast is not on the DEA controlled substances list.

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Schedule check

Schedule sources for Zoryve
Source	What it lists
FDA NDC directory	4 prescription listings from 1 labelers, none with a DEA schedule
DEA controlled substances list	roflumilast is not on the list

Zoryve NDC listings

NDC listings for Zoryve
NDC	Product	Form	Strength	Labeler	DEA schedule
80610-430	ZORYVE	aerosol, foam	3 mg/g	Arcutis Biotherapeutics, Inc.	None
80610-105	ZORYVE	cream	.5 mg/g	Arcutis Biotherapeutics, Inc.	None
80610-115	ZORYVE	cream	1.5 mg/g	Arcutis Biotherapeutics, Inc.	None
80610-130	ZORYVE	cream	3 mg/g	Arcutis Biotherapeutics, Inc.	None

Questions

Is Zoryve a controlled substance?

No. Zoryve (roflumilast) is not a federally controlled substance. None of its FDA NDC listings carries a DEA schedule, and roflumilast is not on the DEA controlled substances list.

Is Zoryve a narcotic?

No. Zoryve (roflumilast) is not on the DEA controlled substances list, so the DEA does not classify it as a narcotic. Its FDA established pharmacologic class is Phosphodiesterase 4 Inhibitor.

Does this page cover state schedules?

No. This page reports the federal schedule only. Some states schedule drugs on their own; check your state board of pharmacy.

Is Zoryve a controlled substance?

Which 2027 plans near you dropped or restricted Zoryve?

Schedule check

Zoryve NDC listings

Questions

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