FDA drug class
Alkylating Drugs list
Every FDA-approved prescription drug the FDA NDC directory tags with the Alkylating Drug [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 15 single-ingredient drugs in this class: bendamustine, busulfan, carmustine, chlorambucil, dacarbazine, ifosfamide, lomustine, lurbinectedin, and more.
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Alkylating Drugs (15)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Bendamustine | Treanda, Bendeka, Vivimusta, Belrapzo | Single ingredient | 17 | Not controlled |
| Busulfan | Myleran | Single ingredient | 9 | Not controlled |
| Carmustine | Gliadel | Single ingredient | 1 | Not controlled |
| Chlorambucil | Leukeran | Single ingredient | 1 | Not controlled |
| Dacarbazine | None listed | Single ingredient | 4 | Not controlled |
| Ifosfamide | Ifex | Single ingredient | 11 | Not controlled |
| Lomustine | Gleostine | Single ingredient | 12 | Not controlled |
| Lurbinectedin | Zepzelca | Single ingredient | 1 | Not controlled |
| Mechlorethamine | Valchlor | Single ingredient | 1 | Not controlled |
| Melphalan | Ivra, Evomela | Single ingredient | 2 | Not controlled |
| Mitomycin | Mutamycin | Single ingredient | 33 | Not controlled |
| Procarbazine | Matulane | Single ingredient | 1 | Not controlled |
| Temozolomide | Temodar | Single ingredient | 71 | Not controlled |
| Thiotepa | Tepadina | Single ingredient | 17 | Not controlled |
| Trabectedin | Yondelis, Evdi | Single ingredient | 2 | Not controlled |
FDA established pharmacologic class: Alkylating Drug [EPC].
Questions
What drugs are Alkylating Drugs?
The FDA NDC directory lists 15 single-ingredient drugs in this class: bendamustine, busulfan, carmustine, chlorambucil, dacarbazine, ifosfamide, lomustine, lurbinectedin, and more.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
- BendamustineTreanda, Bendeka
- BusulfanMyleran
- CarmustineGliadel
- ChlorambucilLeukeran
- DacarbazineFDA label
- IfosfamideIfex
- LomustineGleostine
- LurbinectedinZepzelca
- All drug classesFDA EPC
- Controlled substances by scheduleDEA list
- Generic drug lookupFDA Orange Book
- NDC lookupFDA NDC directory
- Medicare Part D drug coverageBy plan and state