FDA drug class
Biguanides list
Every FDA-approved prescription drug the FDA NDC directory tags with the Biguanide [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 1 single-ingredient drug in this class: metformin. Another 13 combination products include one of them.
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Biguanides (14)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Metformin | Glumetza | Single ingredient | 449 | Not controlled |
| Canagliflozin and metformin | Invokamet, Invokamet XR | Combination | 8 | Not controlled |
| Dapagliflozin and metformin | None listed | Combination | 30 | Not controlled |
| Empagliflozin and metformin | Synjardy | Combination | 8 | Not controlled |
| Empagliflozin, linagliptin and metformin | Trijardy XR | Combination | 4 | Not controlled |
| Glipizide and metformin | None listed | Combination | 21 | Not controlled |
| Glyburide and metformin | None listed | Combination | 30 | Not controlled |
| Linagliptin and metformin | Jentadueto, Jentadueto XR | Combination | 8 | Not controlled |
| Metformin and alogliptin benzoate | Kazano | Combination | 5 | Not controlled |
| Metformin and dapagliflozin propanediol | Xigduo | Combination | 7 | Not controlled |
| Metformin and ertugliflozin pidolate | Segluromet | Combination | 4 | Not controlled |
| Pioglitazone and metformin | Actoplus Met | Combination | 13 | Not controlled |
| Saxagliptin and metformin | None listed | Combination | 6 | Not controlled |
| Sitagliptin and metformin | Janumet, Zituvimet, Zituvimet XR | Combination | 37 | Not controlled |
FDA established pharmacologic class: Biguanide [EPC].
Questions
What drugs are Biguanides?
The FDA NDC directory lists 1 single-ingredient drug in this class: metformin. Another 13 combination products include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
- MetforminGlumetza
- Canagliflozin and metforminInvokamet, Invokamet XR
- Dapagliflozin and metforminFDA label
- Empagliflozin and metforminSynjardy
- Empagliflozin, linagliptin and metforminTrijardy XR
- Glipizide and metforminFDA label
- Glyburide and metforminFDA label
- Linagliptin and metforminJentadueto, Jentadueto XR
- All drug classesFDA EPC
- Controlled substances by scheduleDEA list
- Generic drug lookupFDA Orange Book
- NDC lookupFDA NDC directory
- Medicare Part D drug coverageBy plan and state