FDA label
What is Trijardy XR used for?
Trijardy XR contains empagliflozin, linagliptin and metformin. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “TRIJARDY XR is a combination of empagliflozin, linagliptin, and metformin hydrochloride (HCl) indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.”
Run it in Rivvi
Which 2027 plans near you dropped or restricted Trijardy XR?
Tier changes and new prior auth, step therapy or quantity limits, plan by plan.
Free to start. Opens Rivvi, the AI workspace for healthcare teams.
Trijardy XR, tablet, extended release
Indications and Usage, quoted from the label by Boehringer Ingelheim Pharmaceuticals, Inc. (NDA212614). Cross-references to other label sections are left out.
TRIJARDY XR is a combination of empagliflozin, linagliptin, and metformin hydrochloride (HCl) indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Empagliflozin is indicated to reduce the risk of cardiovascular (CV) death in adults with type 2 diabetes mellitus and established CV disease.
Limitations of Use
TRIJARDY XR is not recommended for use to improve glycemic control in patients with type 1 diabetes mellitus. It may increase the risk of diabetic ketoacidosis in these patients.
TRIJARDY XR has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at an increased risk for the development of pancreatitis while using TRIJARDY XR.
Source: DailyMed label, set id 71873567-9594-452a-bb92-34a129adecac, version 11, effective August 24, 2026. NDC 0597-0380, one of 4 listings for this product.
Questions
What is Trijardy XR used for?
The FDA label says: “TRIJARDY XR is a combination of empagliflozin, linagliptin, and metformin hydrochloride (HCl) indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.”
What drug class is Trijardy XR?
FDA lists empagliflozin, linagliptin and metformin in the Biguanide and Dipeptidyl Peptidase 4 Inhibitor and Sodium-Glucose Cotransporter 2 Inhibitor established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.
More on Trijardy XR
- Is Trijardy XR a controlled substance?Federal schedule
- Generic for Trijardy XRFDA Orange Book
- Biguanides listFDA drug class
- Dipeptidyl Peptidase 4 Inhibitors listFDA drug class
- Sodium-Glucose Cotransporter 2 Inhibitors listFDA drug class
- NDC 0597-0380Trijardy XR NDC record
- NDC 0597-0385Trijardy XR NDC record
- NDC 0597-0390Trijardy XR NDC record