NDC directory
Central Nervous System Depressants list
Every FDA-approved prescription drug the FDA NDC directory tags with the Central Nervous System Depressant [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
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The FDA NDC directory lists 1 single-ingredient drug in this class: sodium oxybate. Another 1 combination product include one of them.
Central Nervous System Depressants (2)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Sodium oxybate | Xyrem, Lumryz | Single ingredient | 9 | Schedule III |
| Sodium oxybate, calcium oxybate, potassium oxybate and magnesium oxybate | Xywav | Combination | 1 | Schedule III |
FDA established pharmacologic class: Central Nervous System Depressant [EPC].
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Questions
What drugs are Central Nervous System Depressants?
The FDA NDC directory lists 1 single-ingredient drug in this class: sodium oxybate. Another 1 combination product include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
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Map Xyrem and your other top fills to their generics
Rivvi lists each brand, its generics in RxNorm, and the brands with no generic.
Map my fillsFree to start. Opens Rivvi, the AI workspace for healthcare teams.
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