FDA drug class
Endothelin Receptor Antagonists list
Every FDA-approved prescription drug the FDA NDC directory tags with the Endothelin Receptor Antagonist [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 6 single-ingredient drugs in this class: ambrisentan, aprocitentan, atrasentan, bosentan, macitentan, sparsentan. Another 1 combination product include one of them.
Run it in Rivvi
Map Letairis and your other top fills to their generics
Every strength in RxNorm, with brands that have no generic flagged.
Build the mapFree to start. Opens Rivvi, the AI workspace for healthcare teams.
Endothelin Receptor Antagonists (7)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Ambrisentan | Letairis | Single ingredient | 26 | Not controlled |
| Aprocitentan | Tryvio | Single ingredient | 1 | Not controlled |
| Atrasentan | Vanrafia | Single ingredient | 1 | Not controlled |
| Bosentan | Tracleer | Single ingredient | 14 | Not controlled |
| Macitentan | Opsumit | Single ingredient | 15 | Not controlled |
| Sparsentan | Filspari | Single ingredient | 2 | Not controlled |
| Macitentan and tadalafil | Opsynvi | Combination | 2 | Not controlled |
FDA established pharmacologic class: Endothelin Receptor Antagonist [EPC].
Questions
What drugs are Endothelin Receptor Antagonists?
The FDA NDC directory lists 6 single-ingredient drugs in this class: ambrisentan, aprocitentan, atrasentan, bosentan, macitentan, sparsentan. Another 1 combination product include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
- AmbrisentanLetairis
- AprocitentanTryvio
- AtrasentanVanrafia
- BosentanTracleer
- MacitentanOpsumit
- SparsentanFilspari
- Macitentan and tadalafilOpsynvi
- All drug classesFDA EPC
- Controlled substances by scheduleDEA list
- Generic drug lookupFDA Orange Book
- NDC lookupFDA NDC directory
- Medicare Part D drug coverageBy plan and state