NDC directory
Histamine-1 Receptor Antagonists list
Every FDA-approved prescription drug the FDA NDC directory tags with the Histamine-1 Receptor Antagonist [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
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The FDA NDC directory lists 9 single-ingredient drugs in this class: alcaftadine, azelastine, bepotastine, carbinoxamine, cetirizine, desloratadine, diphenhydramine, levocetirizine, and more. Another 5 combination products include one of them.
Histamine-1 Receptor Antagonists (14)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Alcaftadine | Lastacaft | Single ingredient | 1 | Not controlled |
| Azelastine | None listed | Single ingredient | 20 | Not controlled |
| Bepotastine | Bepreve | Single ingredient | 8 | Not controlled |
| Carbinoxamine | RyVent, Karbinal, Carbzah | Single ingredient | 10 | Not controlled |
| Cetirizine | Zerviate, Quzyttir | Single ingredient | 21 | Not controlled |
| Desloratadine | Clarinex | Single ingredient | 15 | Not controlled |
| Diphenhydramine | None listed | Single ingredient | 39 | Not controlled |
| Levocetirizine | Xyzal | Single ingredient | 45 | Not controlled |
| Olopatadine | None listed | Single ingredient | 7 | Not controlled |
| Azelastine and fluticasone propionate | Dymista | Combination | 7 | Not controlled |
| Codeine and chlorpheniramine | Tuxarin | Combination | 1 | Schedule III |
| Desloratadine and pseudoephedrine | Clarinex-d 12 Hour | Combination | 1 | Not controlled |
| Hydrocodone and chlorpheniramine | None listed | Combination | 3 | Schedule II |
| Olopatadine and mometasone furoate | Ryaltris | Combination | 2 | Not controlled |
FDA established pharmacologic class: Histamine-1 Receptor Antagonist [EPC].
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Questions
What drugs are Histamine-1 Receptor Antagonists?
The FDA NDC directory lists 9 single-ingredient drugs in this class: alcaftadine, azelastine, bepotastine, carbinoxamine, cetirizine, desloratadine, diphenhydramine, levocetirizine, and more. Another 5 combination products include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
- AzelastineFDA label
- BepotastineBepreve
- CarbinoxamineRyVent, Karbinal
- CetirizineZerviate, Quzyttir
- DesloratadineClarinex
- DiphenhydramineFDA label
- LevocetirizineXyzal
- OlopatadineFDA label
- All drug classesFDA EPC
- Controlled substances by scheduleDEA list
- Generic drug lookupFDA Orange Book
- NDC lookupFDA NDC directory
- Medicare Part D drug coverageBy plan and state
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Map Lastacaft and your other top fills to their generics
Rivvi lists each brand, its generics in RxNorm, and the brands with no generic.
Map my fillsFree to start. Opens Rivvi, the AI workspace for healthcare teams.
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