FDA drug class
Sigma-1 Agonists list
Every FDA-approved prescription drug the FDA NDC directory tags with the Sigma-1 Agonist [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 0 single-ingredient drugs in this class: . Another 4 combination products include one of them.
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Sigma-1 Agonists (4)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Brompheniramine, pseudoephedrine and dextromethorphan | None listed | Combination | 18 | Not controlled |
| Dextromethorphan and bupropion | Auvelity | Combination | 2 | Not controlled |
| Dextromethorphan and quinidine | Nuedexta | Combination | 6 | Not controlled |
| Promethazine and dextromethorphan | None listed | Combination | 18 | Not controlled |
FDA established pharmacologic class: Sigma-1 Agonist [EPC].
Questions
What drugs are Sigma-1 Agonists?
The FDA NDC directory lists 0 single-ingredient drugs in this class: . Another 4 combination products include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
- Brompheniramine, pseudoephedrine and dextromethorphanFDA label
- Dextromethorphan and bupropionAuvelity
- Dextromethorphan and quinidineNuedexta
- Promethazine and dextromethorphanFDA label
- All drug classesFDA EPC
- Controlled substances by scheduleDEA list
- Generic drug lookupFDA Orange Book
- NDC lookupFDA NDC directory
- Medicare Part D drug coverageBy plan and state