FDA label
What is Auvelity used for?
Auvelity contains dextromethorphan and bupropion. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label for Auvelity lists 2 uses: Major Depressive Disorder; Agitation Associated with Dementia Due to Alzheimer’s Disease.
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Auvelity, tablet, multilayer, extended release
Indications and Usage, quoted from the label by Axsome Therapeutics, Inc. (NDA215430). Cross-references to other label sections are left out.
Major Depressive Disorder
AUVELITY is indicated for the treatment of major depressive disorder (MDD) in adults.
Agitation Associated with Dementia Due to Alzheimer’s Disease
AUVELITY is indicated for the treatment of agitation associated with dementia due to Alzheimer’s disease.Limitations of Use:AUVELITY is not indicated as an as needed (“prn”) treatment for agitation associated with dementia due to Alzheimer’s disease.
Source: DailyMed label, set id dcefda7c-9a68-278e-e053-2995a90aec79, version 18, effective August 17, 2026. NDC 81968-030, one of 2 listings for this product.
Questions
What is Auvelity used for?
The FDA label for Auvelity lists 2 uses: Major Depressive Disorder; Agitation Associated with Dementia Due to Alzheimer’s Disease.
What drug class is Auvelity?
FDA lists dextromethorphan and bupropion in the Aminoketone and Sigma-1 Agonist and Uncompetitive N-methyl-D-aspartate Receptor Antagonist established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.