Medicare drug coverage

XIFAXAN: 2027 tier

XIFAXAN is tier 3 on the 5,495 plans that cover it in 2027. 5,495 of 5,495 Part D plans (100%) list XIFAXAN on their 2027 formulary, the plan's list of covered drugs (the same share as 2026). 97% of those require prior authorization, step therapy, or a quantity limit. Plan counts include both Medicare Advantage plans with drug coverage (5,172 MA-PD) and stand-alone drug plans (323 PDP).

Data only, not plan advice. Confirm on Medicare.gov Plan Finder or 1-800-MEDICARE.

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2027 compared with 2026

XIFAXAN is number 41 by total Medicare Part D spending in 2024 ($1.2 billion). Plans that list it most often put it on tier 3 (a tier is the cost level a plan puts a drug on; a lower tier usually costs less). Counts use 3 RxNorm products for this name.

XIFAXAN Part D coverage, 2026 and 2027
Measure20262027Change
Part D plans in the file5,5185,495-23
Plans that list it5,517 (>99%)5,495 (100%)no change
Prior authorization (of plans that list it)5,207 (94%)4,112 (75%)-19 points
Step therapy (of plans that list it)0 (0%)0 (0%)no change
Quantity limit (of plans that list it)2,943 (53%)4,423 (80%)+27 points
Any of the three (of plans that list it)5,357 (97%)5,340 (97%)no change
Left off or restricted (of all plans)5,358 (97%)5,340 (97%)no change

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Every 2027 stand-alone drug plan

Each stand-alone Part D plan (PDP) with XIFAXAN's 2027 tier and limits. CMS files a PDP once per region, so one plan name can have several plan IDs; the row shows the tier and limits most of them use. Medicare Advantage drug plans are local: pick a state for its plan-by-plan table.

XIFAXAN on every 2027 stand-alone Part D plan
Plan (PDP)Plan IDs2027 tier2027 limits
AARP Medicare Rx Preferred from UHC (PDP)39Tier 3PA
AARP Medicare Rx Saver from UHC (PDP)34Tier 3PA
Blue Medicare Rx Enhanced (PDP)1Tier 3PA, QL
Blue Medicare Rx Standard (PDP)1Tier 3PA, QL
Blue MedicareRx Essentials (PDP)1Tier 3PA, QL
Blue MedicareRx Plus (PDP)1Tier 3PA, QL
Blue MedicareRx Premier (PDP)1Tier 3PA on some strengths, QL on some strengths
Blue MedicareRx Value (PDP)1Tier 3PA, QL
Blue MedicareRx Value Plus (PDP)1Tier 3PA on some strengths, QL on some strengths
Blue Shield Rx Enhanced (PDP)1Tier 3PA, QL
Blue Shield Rx Plus (PDP)1Tier 3PA, QL
BlueMedicare Complete Rx (PDP)1Tier 3PA, QL
BlueMedicare Premier Rx (PDP)2Tier 3PA on some strengths, QL on some strengths (1 of 2 IDs)
BlueMedicare Value Rx (PDP)1Tier 3PA on some strengths, QL on some strengths
BlueRx Enhanced Plus (PDP)1Tier 3PA, QL
BlueRx Essential (PDP)1Tier 3PA, QL
HealthSpring Assurance Rx (PDP)35Tier 3PA, QL
HealthSpring Extra Rx (PDP)2Tier 3PA, QL
HealthSpring Extra RX (PDP)3Tier 3PA, QL
Horizon Medicare Blue Rx Enhanced (PDP)1Tier 3PA, QL
Horizon Medicare Blue Rx Standard (PDP)1Tier 3PA, QL
Humana Basic Rx Plan (PDP)34Tier 3PA, QL
Humana Premier Rx Plan (PDP)34Tier 3PA, QL
Humana Value Rx Plan (PDP)34Tier 3PA, QL
MedicareBlue Rx Standard (PDP)1Tier 3PA, QL
Prescription Blue Premium (PDP)1Tier 3PA on some strengths, QL
Prescription Blue Select (PDP)1Tier 3PA on some strengths, QL
SilverScript Choice (PDP)20Tier 3PA, QL on some strengths
Wellcare Classic (PDP)34Tier 2PA, QL
Wellcare Value Script (PDP)34Tier 2PA, QL

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Formulary tier

XIFAXAN formulary tier, 2026 and 2027
Tier2026 plans2027 plans
Tier 1163 (3%)123 (2%)
Tier 26 (<1%)318 (6%)
Tier 3359 (7%)5,054 (92%)
Tier 42,689 (49%)0 (0%)
Tier 52,300 (42%)0 (0%)

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

Plan by plan, 2026 to 2027

4,380 plan IDs are in both files. 1,193 of them (27%) added prior authorization, step therapy, or a quantity limit for XIFAXAN, and 0 stopped listing it.

XIFAXAN: plans in both 2026 and 2027
Plan by planPlans
Same plan ID in both years4,380
Listed it in 2026, not in 20270 (0%)
Listed it in 2027, not in 20260 (0%)
Moved it to a higher tier41 (1%)
Added prior authorization0 (0%)
Added step therapy0 (0%)
Added a quantity limit1,193 (27%)
Added at least one of the three1,193 (27%)
Removed at least one of the three697 (16%)
Plan IDs new in 20271,115
2026 plan IDs not in the 2027 file1,138

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS 2026 Part D formulary file (basic drugs and plan information), as of September 30, 2026. Publisher page

States from most to least restrictive

Share of 2027 Part D plans offered in each state that leave XIFAXAN off the formulary or list it with prior authorization, step therapy, or a quantity limit. 39 states tie for the highest share, 100%; Maryland ranks last at 80%. States at the same share are ordered by the prior authorization or step therapy share; states equal on both shares share a rank, marked Tied.

States from most to least restrictive for XIFAXAN, 2027
RankState2027 plansLeft off or restrictedPrior auth or step therapyChange from 2026
Tied 1Alaska9100%100%no change
Tied 1Montana27100%100%no change
Tied 1North Dakota26100%100%no change
Tied 1South Dakota30100%100%no change
5Minnesota63100%98%no change
6Idaho45100%91%no change
7Kentucky123100%89%no change
Tied 8New Jersey74100%86%no change
Tied 8Rhode Island29100%86%no change
Tied 8South Carolina91100%86%no change
Tied 8Vermont14100%86%no change
Tied 12Maine52100%85%no change
Tied 12Wyoming13100%85%no change
Tied 12Kansas84100%85%no change
15Mississippi105100%84%no change
Tied 16Utah53100%83%no change
Tied 16Arkansas86100%83%no change
Tied 18New Mexico68100%82%no change
Tied 18Texas412100%82%no change
20Delaware43100%81%no change
21Missouri171100%80%no change
Tied 22Florida549100%79%no change
Tied 22Louisiana126100%79%no change
Tied 24Nebraska51100%78%no change
Tied 24Oklahoma81100%78%no change
26Iowa64100%77%no change
Tied 27New Hampshire25100%76%no change
Tied 27Indiana140100%76%no change
Tied 27West Virginia70100%76%no change
Tied 30Illinois133100%75%no change
Tied 30North Carolina177100%75%no change
Tied 32Arizona148100%74%no change
Tied 32Connecticut54100%74%no change
34Ohio173100%73%no change
35Massachusetts92100%72%no change
36Tennessee157100%69%no change
37Alabama115100%63%no change
38Michigan183100%61%no change
39Pennsylvania324100%53%no change
40Wisconsin9799%91%no change
41Nevada10097%97%-3 points
42Virginia14596%83%no change
43Georgia15195%81%no change
44Oregon9295%62%no change
45Colorado10690%66%+3 points
46New York21590%59%+1 point
47California39788%84%no change
48Hawaii5088%40%no change
49District of Columbia2186%81%-2 points
50Washington11486%61%+1 point
51Maryland4980%41%-4 points

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

By parent organization

164 parent organizations offer 2027 Part D plans. Humana Inc. has the most, 884, and 100% of them leave XIFAXAN off or restrict it.

XIFAXAN coverage by parent organization, 2027
Parent organization2027 plans ↓List itRestrict it (of listing)Left off or restrictedChange from 2026Plans that added a restriction
Lifetime Healthcare, Inc.21100%0%0%no change0
Athena Healthcare Holdings, LLC19100%100%100%no change0
Mitchell Family Office19100%100%100%no change0
Risant Health, Inc.17100%100%100%no change15
Champion Health Plans-USA, LLC.16100%100%100%no change0
MEDICAL MUTUAL OF OHIO16100%100%100%no change0
Ultimate Healthcare Holdings, LLC16100%100%100%no change15
Gold Kidney Health Plan15100%100%100%no change0
Trinity Health Corporation15100%100%100%no change14
CuraCor Solutions Corp.14100%100%100%no change0
Lumeris Group Holdings Corporation14100%100%100%no change0
Rifkin Managed Care Holding, LLC14100%100%100%no change7
Sanford Health14100%100%100%no change8
University of Wisconsin Hospitals and Clincs Autho14100%100%100%no change14
Cambia Health Solutions, Inc.13100%100%100%no change0
Clover Health Holdings, Inc.13100%100%100%no change13
Henry Ford Health System13100%100%100%no change0
Curana Health Holdings, LLC12100%100%100%no change0
Fallon Community Health Plan, Inc.12100%100%100%no change0
Louisiana Health Service & Indemnity Company12100%100%100%no change0
ATRIO Health Plans11100%100%100%no change0
Aware Integrated, Inc.10100%100%100%no change0
Gemstone Holdings, Inc.10100%100%100%no change0
Intermountain Health Care, Inc.10100%100%100%no change0
Thomas Jefferson University10100%100%100%no change0

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Near it by Part D spending

Pharmacies near you

Enter a ZIP to see the lists for your area. From the NPPES NPI Registry. These lists do not show plan networks.

About this data

A plan here is one Part D plan as the CMS formulary files list it: contract, plan, and segment. That covers Medicare Advantage plans with drug coverage and stand-alone drug plans. A plan lists a drug when its formulary has a row for any RxNorm product of that name. When it has several, the row with the lowest tier is the one counted, and restricted means that row has prior authorization, step therapy, or a quantity limit.

A plan with no row for the drug counts as not listing it. That can be a product the file codes another way, so read a low count as a lookup result, not a coverage decision. A state counts every plan the CMS landscape file offers there. Parent organizations are named as CMS names them. The drug list is the top 200 by total Part D spending.

Source: CMS 2027 Part D formulary file (basic drugs and plan information), as of October 8, 2026. Publisher page

Source: CMS CY2027 landscape file (states and parent organizations), as of September 30, 2026. Publisher page

Source: CMS Medicare Part D Spending by Drug, 2024 data, as of June 25, 2026. Publisher page

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