FDA label
What is Adempas used for?
Adempas contains riociguat. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label for Adempas lists 2 uses: Chronic-Thromboembolic Pulmonary Hypertension; Pulmonary Arterial Hypertension.
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Adempas, tablet, film coated
Indications and Usage, quoted from the label by Bayer HealthCare Pharmaceuticals Inc. (NDA204819). Cross-references to other label sections are left out.
Chronic-Thromboembolic Pulmonary Hypertension
Adempas is indicated for the treatment of adults with persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH), (WHO Group 4) after surgical treatment, or inoperable CTEPH, to improve exercise capacity and WHO functional class.
Pulmonary Arterial Hypertension
Adempas is indicated for the treatment of adults with pulmonary arterial hypertension (PAH), (WHO Group 1), to improve exercise capacity, WHO functional class and to delay clinical worsening.
Efficacy was shown in patients on Adempas monotherapy or in combination with endothelin receptor antagonists or prostanoids. Studies establishing effectiveness included predominately patients with WHO functional class II–III and etiologies of idiopathic or heritable PAH (61%) or PAH associated with connective tissue diseases (25%).
Source: DailyMed label, set id 7b57509a-3d5d-41d4-8fed-1471e26372a3, version 32, effective August 13, 2026. NDC 50419-250, one of 5 listings for this product.
Questions
What is Adempas used for?
The FDA label for Adempas lists 2 uses: Chronic-Thromboembolic Pulmonary Hypertension; Pulmonary Arterial Hypertension.
What drug class is Adempas?
FDA lists riociguat in the Soluble Guanylate Cyclase Stimulator established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.