FDA label
What is Climara used for?
Climara contains estradiol. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label for Climara lists 4 uses: Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause; Treatment of Moderate to Severe Symptoms of Vulvar and Vaginal Atrophy due to Menopause; Treatment of Hypoestrogenism due to Hypogonadism, Castration, or Primary Ovarian Failure; Prevention of Postmenopausal Osteoporosis.
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Climara, patch
Indications and Usage, quoted from the label by Bayer HealthCare Pharmaceuticals Inc. (NDA020375). Cross-references to other label sections are left out.
Climara is indicated for:
Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause
Treatment of Moderate to Severe Symptoms of Vulvar and Vaginal Atrophy due to Menopause
Limitation of Use
When prescribing solely for the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause, first consider the use of topical vaginal products.
Treatment of Hypoestrogenism due to Hypogonadism, Castration, or Primary Ovarian Failure
Prevention of Postmenopausal Osteoporosis
Limitation of Use
When prescribing solely for the prevention of postmenopausal osteoporosis, first consider the use of non-estrogen medications. Consider estrogen therapy only for women at significant risk of osteoporosis.
Source: DailyMed label, set id 1e9702c4-f2d7-4ea8-b6e8-7dca31671864, version 25, effective March 26, 2026. NDC 50419-451, one of 6 listings for this product.
Questions
What is Climara used for?
The FDA label for Climara lists 4 uses: Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause; Treatment of Moderate to Severe Symptoms of Vulvar and Vaginal Atrophy due to Menopause; Treatment of Hypoestrogenism due to Hypogonadism, Castration, or Primary Ovarian Failure; Prevention of Postmenopausal Osteoporosis.
What drug class is Climara?
FDA lists estradiol in the Estrogen established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.
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