FDA label
What is Combigan used for?
Combigan contains brimonidine and timolol. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “COMBIGAN® is indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP.”
Run it in Rivvi
Which 2027 plans near you dropped or restricted Combigan?
Tier changes and new prior auth, step therapy or quantity limits, plan by plan.
Free to start. Opens Rivvi, the AI workspace for healthcare teams.
Combigan, solution/ drops
Indications and Usage, quoted from the label by Allergan, Inc. (NDA021398). Cross-references to other label sections are left out.
COMBIGAN® is indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP.
The IOP-lowering of COMBIGAN dosed twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol maleate ophthalmic solution dosed twice a day and 0.2% brimonidine tartrate ophthalmic solution dosed three times per day.
Source: DailyMed label, set id feaf1480-a4b8-4486-992a-96be3a596243, version 22, effective March 17, 2026. NDC 0023-9211, one of 1 listing for this product.
Questions
What is Combigan used for?
The FDA label says: “COMBIGAN® is indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP.”
What drug class is Combigan?
FDA lists brimonidine and timolol in the alpha-Adrenergic Agonist and beta-Adrenergic Blocker established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.
More on Combigan
- Is Combigan a controlled substance?Federal schedule
- Generic for CombiganFDA Orange Book
- What is Brimonidine and Timolol used for?FDA label uses
- Is Brimonidine and Timolol a controlled substance?Federal schedule
- Alpha-Adrenergic Agonists listFDA drug class
- Beta Blockers listFDA drug class
- NDC 0023-9211Combigan NDC record