FDA drug class
Alpha-Adrenergic Agonists list
Every FDA-approved prescription drug the FDA NDC directory tags with the alpha-Adrenergic Agonist [EPC] class, with brand names and DEA schedules.
Source: FDA NDC Directory file dated 2026-10-22. Publisher page
The FDA NDC directory lists 5 single-ingredient drugs in this class: apraclonidine, brimonidine, ephedrine, epinephrine, midodrine. Another 9 combination products include one of them.
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Alpha-Adrenergic Agonists (14)
| Drug | Brand names | Type | NDC listings | DEA schedule |
|---|---|---|---|---|
| Apraclonidine | Iopidine 1% | Single ingredient | 2 | Not controlled |
| Brimonidine | Alphagan P, Mirvaso | Single ingredient | 33 | Not controlled |
| Ephedrine | Emerphed, Akovaz | Single ingredient | 38 | Not controlled |
| Epinephrine | Adrenalin, Auvi-Q, neffy, Epipen | Single ingredient | 116 | Not controlled |
| Midodrine | None listed | Single ingredient | 109 | Not controlled |
| Articaine and epinephrine | Orabloc | Combination | 28 | Not controlled |
| Brimonidine and timolol | Combigan | Combination | 21 | Not controlled |
| Brinzolamide and brimonidine | Simbrinza | Combination | 1 | Not controlled |
| Brompheniramine, pseudoephedrine and dextromethorphan | None listed | Combination | 18 | Not controlled |
| Bupivacaine and epinephrine | Vivacaine, Marcaine with Epinephrine | Combination | 27 | Not controlled |
| Carbachol and brimonidine | Yuvezzi | Combination | 1 | Not controlled |
| Desloratadine and pseudoephedrine | Clarinex-d 12 Hour | Combination | 1 | Not controlled |
| Lidocaine and epinephrine | Flavalta | Combination | 60 | Not controlled |
| Prilocaine and epinephrine | Citanest Forte DENTAL | Combination | 2 | Not controlled |
FDA established pharmacologic class: alpha-Adrenergic Agonist [EPC].
Questions
What drugs are Alpha-Adrenergic Agonists?
The FDA NDC directory lists 5 single-ingredient drugs in this class: apraclonidine, brimonidine, ephedrine, epinephrine, midodrine. Another 9 combination products include one of them.
Where does this list come from?
From the established pharmacologic class (EPC) field FDA publishes for each listing in the NDC directory. A drug is listed when most of its prescription listings carry the class.
Related
- ApraclonidineIopidine 1%
- BrimonidineAlphagan P, Mirvaso
- EphedrineEmerphed, Akovaz
- EpinephrineAdrenalin, Auvi-Q
- MidodrineFDA label
- Articaine and epinephrineOrabloc
- Brimonidine and timololCombigan
- Brinzolamide and brimonidineSimbrinza
- All drug classesFDA EPC
- Controlled substances by scheduleDEA list
- Generic drug lookupFDA Orange Book
- NDC lookupFDA NDC directory
- Medicare Part D drug coverageBy plan and state