FDA label
What is Simbrinza used for?
Simbrinza contains brinzolamide and brimonidine. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “SIMBRINZA (brinzolamide/brimonidine tartrate ophthalmic suspension) 1%/0.2% is a fixed combination of a carbonic anhydrase inhibitor and an alpha 2 adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.”
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Simbrinza, suspension/ drops
Indications and Usage, quoted from the label by Alcon Laboratories, Inc. (NDA204251). Cross-references to other label sections are left out.
SIMBRINZA (brinzolamide/brimonidine tartrate ophthalmic suspension) 1%/0.2% is a fixed combination of a carbonic anhydrase inhibitor and an alpha 2 adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Source: DailyMed label, set id a49c157e-6310-0011-7b7f-e26fc1820d59, version 19, effective March 11, 2025. NDC 0065-4147, one of 1 listing for this product.
Questions
What is Simbrinza used for?
The FDA label says: “SIMBRINZA (brinzolamide/brimonidine tartrate ophthalmic suspension) 1%/0.2% is a fixed combination of a carbonic anhydrase inhibitor and an alpha 2 adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.”
What drug class is Simbrinza?
FDA lists brinzolamide and brimonidine in the Carbonic Anhydrase Inhibitor and alpha-Adrenergic Agonist established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.