FDA label

What is epinephrine used for?

The FDA-approved uses of epinephrine, quoted from the Indications and Usage section of its DailyMed label.

Source: DailyMed SPL label file dated 2026-10-23. Publisher page

The FDA label for epinephrine (injection) lists 2 uses: Hypotension associated with Septic Shock; Anaphylaxis.

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Epinephrine, injection

Indications and Usage, quoted from the label by Gland Pharma Limited (ANDA219239). Cross-references to other label sections are left out.

Hypotension associated with Septic Shock

Epinephrine Injection, 1 mg/mL is indicated to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.

Anaphylaxis

Emergency treatment of allergic reactions (Type I), including anaphylaxis, which may result from allergic reactions to insect stings, biting insects, foods, drugs, sera, diagnostic testing substances and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis. The signs and symptoms associated with anaphylaxis include flushing, apprehension, syncope, tachycardia, thready or unobtainable pulse associated with hypotension, convulsions, vomiting, diarrhea and abdominal cramps, involuntary voiding, airway swelling, laryngospasm, bronchospasm, pruritus, urticaria or angioedema, swelling of the eyelids, lips, and tongue.

Source: DailyMed label, set id 79ca73ca-d3c0-40af-9dec-e2f4ce669cda, version 6, effective September 23, 2026. NDC 68083-633, one of 19 listings for this product.

Epinephrine, injection, solution, concentrate

Indications and Usage, quoted from the label by Fresenius Kabi USA, LLC (ANDA213708). Cross-references to other label sections are left out.

Hypotension associated with Septic Shock

Epinephrine Injection USP, 1 mg/mL is indicated to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.

Anaphylaxis

Emergency treatment of allergic reactions (Type I), including anaphylaxis, which may result from allergic reactions to insect stings, biting insects, foods, drugs, sera, diagnostic testing substances and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis. The signs and symptoms associated with anaphylaxis include flushing, apprehension, syncope, tachycardia, thready or unobtainable pulse associated with hypotension, convulsions, vomiting, diarrhea and abdominal cramps, involuntary voiding, airway swelling, laryngospasm, bronchospasm, pruritus, urticaria or angioedema, swelling of the eyelids, lips, and tongue.

Induction and Maintenance of Mydriasis during Intraocular Surgery

Induction and maintenance of mydriasis during intraocular surgery.

Source: DailyMed label, set id a6afb9e8-1db9-480c-8d31-58c5c870ca49, version 2, effective July 29, 2026. NDC 63323-696, one of 4 listings for this product.

Epinephrine, injection, solution

Indications and Usage, quoted from the label by American Regent, Inc. (ANDA207568). Cross-references to other label sections are left out.

Anaphylaxis

Emergency treatment of allergic reactions (Type I), including anaphylaxis, which may result from insect stings or bites, foods, drugs, sera, diagnostic testing substances and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis.

Hypotension associated with Septic Shock

Epinephrine injection is indicated to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.

Source: DailyMed label, set id 6add7604-71f6-4d8a-9447-17ad01fa839d, version 4, effective October 1, 2023. NDC 0517-1171, one of 1 listing for this product.

Questions

What is epinephrine used for?

The FDA label for epinephrine (injection) lists 2 uses: Hypotension associated with Septic Shock; Anaphylaxis.

What drug class is epinephrine?

FDA lists epinephrine in the Catecholamine and alpha-Adrenergic Agonist and beta-Adrenergic Agonist established pharmacologic class.

Does this page cover off-label uses or dosing?

No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.

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