What Is Medroxyprogesterone Acetate Used For?

The FDA label says: “Medroxyprogesterone acetate tablets, USP are indicated for the treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as fibroids or uterine cancer. They are also indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving daily oral conjugated estrogens 0...”

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Medroxyprogesterone Acetate, tablet

Indications and Usage, quoted from the label by Teva Pharmaceuticals USA, Inc. (ANDA040159). Cross-references to other label sections are left out.

Medroxyprogesterone acetate tablets, USP are indicated for the treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as fibroids or uterine cancer. They are also indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving daily oral conjugated estrogens 0.625 mg tablets.

Source: DailyMed label, set id 9eb200b0-db96-4a51-87ea-04db862978c8, version 17, effective March 1, 2024. NDC 0555-0779, one of 23 listings for this product.

Medroxyprogesterone Acetate, injection, suspension

Indications and Usage, quoted from the label by Amneal Pharmaceuticals LLC (ANDA215397). Cross-references to other label sections are left out.

Medroxyprogesterone acetate injectable suspension is indicated for use by females of reproductive potential to prevent pregnancy.
Limitations of Use:
The use of medroxyprogesterone acetate injectable suspension is not recommended as a long-term (i.e. longer than 2 years) birth control method unless other options are considered inadequate.

Source: DailyMed label, set id 6457d70a-2f25-4935-8511-726d988f7a03, version 7, effective January 19, 2026. NDC 70121-1467, one of 11 listings for this product.

Medroxyprogesterone Acetate, injection, suspension, extended release

Indications and Usage, quoted from the label by Amphastar Pharmaceuticals, Inc. (ANDA077235). Cross-references to other label sections are left out.

Medroxyprogesterone acetate is indicated for use by females of reproductive potential to prevent pregnancy.
Limitations of Use: The use of Medroxyprogesterone acetate is not recommended as a long-term (i.e., longer than 2 years) birth control method unless other options are considered inadequate.

Source: DailyMed label, set id fda1aa8a-5739-482a-b4f6-9741ef4d9977, version 9, effective January 1, 2026. NDC 0548-5400, one of 2 listings for this product.

Questions

What is medroxyprogesterone acetate used for?

The FDA label says: “Medroxyprogesterone acetate tablets, USP are indicated for the treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as fibroids or uterine cancer. They are also indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving daily oral conjugated estrogens 0...”

What drug class is medroxyprogesterone acetate?

FDA lists medroxyprogesterone acetate in the Progestin established pharmacologic class.

Does this page cover off-label uses or dosing?

No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.