What is methenamine hippurate used for?

Indications and Usage, quoted from the label by Jubilant Cadista Pharmaceuticals Inc. (ANDA217675). Cross-references to other label sections are left out.

Methenamine hippurate tablets, USP is indicated for prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug should only be used after eradication of the infection by other appropriate antimicrobial agents.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of methenamine hippurate tablets, USP and other antibacterial drugs, methenamine hippurate tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Source: DailyMed label, set id 4263d826-7de2-4011-b8ec-ba1f5222f0e6, version 2, effective February 3, 2026. NDC 59746-797, one of 10 listings for this product.